• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Upar Antiserum (PLAUR) Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS135482

Polyclonal antiserum (host sheep) to soluble mouse uPAR, His tagged. Licensed under United States Patent 5,519,120. More details

$710 / 1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
uPAR antiserum (PLAUR), Polyclonal Antibody
Full Product Name
Sheep anti mouse uPAR antiserum
Product Gene Name
anti-PLAUR antibody
Clonality
Polyclonal
Isotype
IgG
Host
Host: Sheep; Source: Sheep serum
Species Reactivity
Mouse
Form/Format
Frozen liquid
Purity/Purification
Serum
Concentration
Whole Antiserum (lot specific)
Preparation and Storage
Store at -70 degree C. Shelf Life: 5 years from delivery
Molecular Weight
35,428 Da
Chromosome Location
Chromosome: 7; NC_000073.6 (24462500..24475873). Location: 7 A3; 7
3D Structure
ModBase 3D Structure for P35456
Immunogen
Recombinant full length mouse protein fused to a His tag at N-terminal end (Glycosylated).
Target Information
Recognizes soluble urokinase receptor (sUPAR)
Target Molecular Weight
33000

Product Categories/Family for anti-PLAUR antibody

Urokinase (uPA); Polyclonal Antibodies to Mouse uPAR
Applications Tested/Suitable for anti-PLAUR antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-PLAUR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLAUR purchase

MBS135482 is an antibody targeting PLAUR. Also known as Sheep anti mouse uPAR antiserum. Reactive in Mouse. Host: Sheep; Source: Sheep serum.

Additional Details

NCBI/Uniprot data below describe general gene information for PLAUR. It may not necessarily be applicable to this product.

NCBI GI #
7242179
NCBI GeneID
18793
NCBI Accession #
NP_035243.1
UniProt Primary Accession #
P35456
UniProt Secondary Accession #
P35457
UniProt Related Accession #
P35456
GenBank Nucleotide #
NM_011113.3
NCBI Official Full Name
urokinase plasminogen activator surface receptor
NCBI Official Synonym Full Names
plasminogen activator, urokinase receptor
NCBI Official Symbol
Plaur
NCBI Official Synonym Symbols
Cd87; uPAR; u-PAR
UniProt Protein Name
Urokinase plasminogen activator surface receptor
Protein Family
Urokinase plasminogen activator surface receptor
UniProt Gene Name
Plaur
UniProt Synonym Gene Names
U-PAR; uPAR
UniProt Entry Name
UPAR_MOUSE
NCBI Protein Information
urokinase plasminogen activator surface receptor; urokinase plasminogen activator receptor; urokinase-type plasminogen activator receptor

UniProt Comments for PLAUR

uPAR: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2. Expressed in neurons of the rolandic area of the brain. Expressed in the brain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Receptor, misc.

Cellular Component: focal adhesion; membrane; integral to plasma membrane; extracellular region; plasma membrane

Molecular Function: protein domain specific binding; protein binding; enzyme binding; U-plasminogen activator receptor activity; receptor binding

Biological Process: mesenchymal cell differentiation; negative regulation of apoptosis
Show more

Research Articles on PLAUR

1. Importance of vitronectin and its interaction with the urokinase receptor in tumor growth.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PLAUR antibody

 Products by Pathway  Pathway Diagram
 Attachment Of GPI Anchor To UPAR Pathway antibodies  Attachment Of GPI Anchor To UPAR Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Dissolution Of Fibrin Clot Pathway antibodies  Dissolution Of Fibrin Clot Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 PodNet: Protein-protein Interactions In The Podocyte Pathway antibodies  PodNet: Protein-protein Interactions In The Podocyte Pathway Diagram
 Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies  Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram

Diseases associated with anti-PLAUR antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >805 publications with PLAUR and Neoplasms
 Carcinoma Antibodies  >309 publications with PLAUR and Carcinoma
 Neoplasm Invasiveness Antibodies  >259 publications with PLAUR and Neoplasm Invasiveness
 Neoplasm Metastasis Antibodies  >228 publications with PLAUR and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >162 publications with PLAUR and Breast Neoplasms
 Inflammation Antibodies  >107 publications with PLAUR and Inflammation
 Lung Diseases Antibodies  >89 publications with PLAUR and Lung Diseases
 Nervous System Diseases Antibodies  >80 publications with PLAUR and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >80 publications with PLAUR and Cardiovascular Diseases
 Lung Neoplasms Antibodies  >75 publications with PLAUR and Lung Neoplasms

Organs/Tissues associated with anti-PLAUR antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >144 publications with PLAUR and Lung
 Liver Antibodies  >82 publications with PLAUR and Liver
 Embryonic Tissue Antibodies  >79 publications with PLAUR and Embryonic Tissue
 Kidney Antibodies  >67 publications with PLAUR and Kidney
 Skin Antibodies  >63 publications with PLAUR and Skin
 Bone Marrow Antibodies  >43 publications with PLAUR and Bone Marrow
 Connective Tissue Antibodies  >31 publications with PLAUR and Connective Tissue
 Spleen Antibodies  >16 publications with PLAUR and Spleen
 Thyroid Antibodies  >12 publications with PLAUR and Thyroid
 Mammary Gland Antibodies  >7 publications with PLAUR and Mammary Gland
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000