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Dual Specificity Protein Phosphatase 7 (DUSP7) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1368700

MBS1368700 is a recombinant protein targeting DUSP7. Also known as Recombinant Human Dual specificity protein phosphatase 7 (DUSP7). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1160 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dual specificity protein phosphatase 7 (DUSP7), Recombinant Protein
Full Product Name
Recombinant Human Dual specificity protein phosphatase 7 (DUSP7)
Product Gene Name
DUSP7 recombinant protein
Product Synonym Gene Name
DUSP7
Sequence
MKNQLRGPPA RAHMSTSGAA AAGGTRAGSE PGAGSGSGAG TGAGAATGAG AMPCKSAEWL QEELEARGGA SLLLLDCRPH ELFESSHIET AINLAIPGLM LRRLRKGNLP IRSIIPNHAD KERFATRCKA ATVLLYDEAT AEWQPEPGAP ASVLGLLLQK LRDDGCQAYY LQGGFNKFQT EYSEHCETNV DSSSSPSSSP PTSVLGLGGL RISSDCSDGE SDRELPSSAT ESDGSPVPSS QPAFPVQILP YLYLGCAKDS TNLDVLGKYG IKYILNVTPN LPNAFEHGGE FTYKQIPISD HWSQNLSQFF PEAISFIDEA RSKKCGVLVH CLAGISRSVT VTVAYLMQKM NLSLNDAYDF VKRKKSNISP NFNFMGQLLD FERTLGLSSP CDNHASSEQL YFSTPTNHNL FPLNTLEST
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
40,551 Da
Sequence Positions
1-419, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
602749
3D Structure
ModBase 3D Structure for Q16829
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DUSP7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DUSP7. It may not necessarily be applicable to this product.

NCBI GI #
238231453
NCBI GeneID
1849
NCBI Accession #
NP_001938.2
UniProt Primary Accession #
Q16829
UniProt Secondary Accession #
Q2M3J7; Q8NFJ0
UniProt Related Accession #
Q16829
GenBank Nucleotide #
NM_001947.3
NCBI Official Full Name
dual specificity protein phosphatase 7
NCBI Official Synonym Full Names
dual specificity phosphatase 7
NCBI Official Symbol
DUSP7
NCBI Official Synonym Symbols
MKPX; PYST2
UniProt Protein Name
Dual specificity protein phosphatase 7
UniProt Synonym Protein Names
Dual specificity protein phosphatase PYST2
Protein Family
Dual specificity protein phosphatase
UniProt Gene Name
DUSP7
UniProt Synonym Gene Names
PYST2
NCBI Protein Information
dual specificity protein phosphatase 7

NCBI Summary for DUSP7

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]
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UniProt Comments for DUSP7

Regulates the activity of the MAP kinase family in response to changes in the cellular environment. PYST2-S may act as a negative regulator of PYST2-L although it is unclear whether this is by competing for transcription, translation or activation factors.

Research Articles on DUSP7

1. While the low expression level of DUSP7 was restricted to patients with positive rheumatoid factor and anti-citrullinated protein antibodies, the altered expression of CDC25B correlated with the activity of early arthritis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with DUSP7 recombinant protein

 Reference Product  PubMed Publications
 MAPK1 recombinant protein  >3 publications with DUSP7 and MAPK1
 MAPK3 recombinant protein  >2 publications with DUSP7 and MAPK3
 MAPK12 recombinant protein  >1 publications with DUSP7 and MAPK12
 MAPK14 recombinant protein  >1 publications with DUSP7 and MAPK14
 MAPK8 recombinant protein  >1 publications with DUSP7 and MAPK8

Pathways associated with DUSP7 recombinant protein

 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 ERK/MAPK Targets Pathway antibodies  ERK/MAPK Targets Pathway Diagram
 ERKs Are Inactivated Pathway antibodies  ERKs Are Inactivated Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 MAP Kinase Activation In TLR Cascade Pathway antibodies  MAP Kinase Activation In TLR Cascade Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Targets/ Nuclear Events Mediated By MAP Kinases Pathway antibodies  MAPK Targets/ Nuclear Events Mediated By MAP Kinases Pathway Diagram

Diseases associated with DUSP7 recombinant protein

 Disease Name  Pubmed Publications
 Seizures Antibodies  >1 publications with DUSP7 and Seizures
 Lung Neoplasms Antibodies  >1 publications with DUSP7 and Lung Neoplasms
 Brain Diseases Antibodies  >1 publications with DUSP7 and Brain Diseases
 Nervous System Diseases Antibodies  >1 publications with DUSP7 and Nervous System Diseases
 Inflammation Antibodies  >1 publications with DUSP7 and Inflammation

Organs/Tissues associated with DUSP7 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >2 publications with DUSP7 and Bone
 Blood Antibodies  >2 publications with DUSP7 and Blood
 Lung Antibodies  >1 publications with DUSP7 and Lung
 Brain Antibodies  >1 publications with DUSP7 and Brain
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