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Endothelial Cell-Specific Chemotaxis Regulator (ECSCR) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1369916

MBS1369916 is a recombinant protein targeting ECSCR. Also known as Recombinant Human Endothelial cell-specific chemotaxis regulator (ECSCR), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1160 / 0.5 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Endothelial cell-specific chemotaxis regulator (ECSCR), Recombinant Protein
Full Product Name
Recombinant Human Endothelial cell-specific chemotaxis regulator (ECSCR), partial
Product Gene Name
Product Synonym Gene Name
ECSCR
Sequence
QPTMTQ TSSSQGGLGG LSLTTEPVSS NPGYIPSSEA NRPSHLSSTG TPGAGVPSSG RDGGTSRDTF QTVPPNSTTM SLSMREDATI LPSPTSETVL TVAA
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
21,295 Da
Sequence Positions
25-124
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q19T08
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ECSCR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ECSCR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
endothelial cell-specific chemotaxis regulator isoform 1
NCBI Official Synonym Full Names
endothelial cell surface expressed chemotaxis and apoptosis regulator
NCBI Official Symbol
ECSCR
NCBI Official Synonym Symbols
ARIA; ECSM2
UniProt Protein Name
Endothelial cell-specific chemotaxis regulator
UniProt Synonym Protein Names
Apoptosis regulator through modulating IAP expression; ARIA; Endothelial cell-specific molecule 2
UniProt Gene Name
ECSCR
UniProt Synonym Gene Names
ECSM2; ARIA
NCBI Protein Information
endothelial cell-specific chemotaxis regulator

NCBI Summary for ECSCR

The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
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UniProt Comments for ECSCR

Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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