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Interleukin-4 Receptor Subunit Alpha (IL4R) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1375403

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells.… More details

$1340 / 0.5 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interleukin-4 receptor subunit alpha (Il4r), Recombinant Protein
Full Product Name
Recombinant Rat Interleukin-4 receptor subunit alpha (Il4r), partial
Product Gene Name
Product Synonym Gene Name
Il4r
Sequence
IKVLG DPTCFSDYIR TSTCEWQLDS TVDCSSQLLL DYRLLFEFSE NLTCTPKNSA DTVCVCQMAI EEPIQADTYW LELWSERGQL WQGSFKPSDN VKPPAPDNLT LHTNVSNALL LMWSNPYPSN NFLHKGLICM VNISREDNPA EFKVYNVTYT EPKLSFPVNT LTSGVRYRAR VRVLSQSFPG IWSEWSPSIT WYNHFQLPLL QR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
26,001 Da
Sequence Positions
26-232
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q63257
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Il4r recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Il4r purchase

MBS1375403 is a recombinant protein targeting Il4r. Also known as Recombinant Rat Interleukin-4 receptor subunit alpha (Il4r), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Il4r. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-4 receptor subunit alpha
NCBI Official Synonym Full Names
interleukin 4 receptor
NCBI Official Symbol
Il4r
NCBI Official Synonym Symbols
Il4ra
UniProt Protein Name
Interleukin-4 receptor subunit alpha
UniProt Synonym Protein Names
CD_antigen: CD124
UniProt Gene Name
Il4r
UniProt Synonym Gene Names
Il4ra; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA
NCBI Protein Information
interleukin-4 receptor subunit alpha

NCBI Summary for Il4r

a receptor for the cytokine IL-4 [RGD, Feb 2006]

UniProt Comments for Il4r

Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2 ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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