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anti-SERPINA12 antibody :: Goat SERPINA12 Polyclonal Antibody

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Catalog # MBS421823
Unit / Price
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  0.1 mg  /  $300 +1 FREE 8GB USB
Western Blot (WB)
Product Name

SERPINA12, Polyclonal Antibody

Full Product Name

Goat anti-SERPINA12 Antibody

Product Synonym Names
SERPINA12; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12; OL-64; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12; vaspin; visceral adipose-specific SERPIN; SERPINA12 antibody; serpin peptidase inhibitor; clade A (alpha-1 antiproteinase; antitrypsin); member 12 antibody; OL-64 antibody; serine (or cysteine) proteinase inhibitor; clade A (alpha-1 antiproteinase; antitrypsin); member 12 antibody; vaspin antibody; visceral adipose-specific SERPIN antibody
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
RARWKHEFDP NVTK
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-RARWKHEFDPNVTK, from the internal region of the protein sequence according to NP_776249.1.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-SERPINA12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SERPINA12 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-SERPINA12 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 48kDa band observed in Human Adipose lysates (calculated MW of 47.2kDa according to NP_776249.1). Recommended concentration: 0.3-1ug/ml.

Western Blot (WB) of anti-SERPINA12 antibody
(0.5ug/ml) staining of Human Adipose lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-SERPINA12 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for SERPINA12. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Related Accession #
Molecular Weight
47,175 Da
NCBI Official Full Name
serpin A12
NCBI Official Synonym Full Names
serpin family A member 12
NCBI Official Symbol
SERPINA12  [Similar Products]
NCBI Official Synonym Symbols
OL-64
  [Similar Products]
NCBI Protein Information
serpin A12
UniProt Protein Name
Serpin A12
UniProt Synonym Protein Names
OL-64; Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin
Protein Family
UniProt Gene Name
SERPINA12  [Similar Products]
UniProt Synonym Gene Names
Vaspin  [Similar Products]
UniProt Entry Name
SPA12_HUMAN
UniProt Comments for SERPINA12
SERPINA12: May modulate insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues. Belongs to the serpin family.

Protein type: Secreted, signal peptide; Inhibitor; Secreted

Chromosomal Location of Human Ortholog: 14q32.13

Cellular Component: extracellular space; plasma membrane

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: glucose metabolic process; negative regulation of gluconeogenesis; negative regulation of lipid biosynthetic process; positive regulation of insulin receptor signaling pathway; positive regulation of phosphoinositide 3-kinase cascade
Research Articles on SERPINA12
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-SERPINA12 antibody
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