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3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase (A49L) Variola Virus Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1389313

MBS1389313 is a recombinant protein targeting A49L. Also known as Recombinant Variola virus 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (A49L). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$865 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (A49L), Recombinant Protein
Full Product Name
Recombinant Variola virus 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (A49L)
Product Gene Name
Product Synonym Gene Name
A49L
Sequence
MEAIGPNKHG NPFIGHEHTL YDISPGHVYA KSKRMVEQLV TKANNSVIMN GAKLYTCCLR PTGIYGGGDK LTKVFYEQCT QHGNIMYRTV DDDAVHSRVY VGNVAWMHVL AVKYIQYPGS EIKGNAYFCY GYSPSCSYDM FNLLLMKPLG IEQGSRIPRW MLKMYTCKND MKRILFRKPS LLNNYTLKIS NTTFEARQQC RTRFQLLPYL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
24,163 Da
Sequence Positions
1-210, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q89187
Species
Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of A49L recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for A49L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
GenBank Nucleotide #
NCBI Official Full Name
hypothetical protein VARVgp155
NCBI Official Symbol
A49L
UniProt Protein Name
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
UniProt Synonym Protein Names
3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC:1.1.1.145)Alternative name(s):3-beta-hydroxy-5-ene steroid dehydrogenase; Progesterone reductase
UniProt Gene Name
A49L
UniProt Synonym Gene Names
3-beta-HSD
NCBI Protein Information
A49L

UniProt Comments for A49L

Catalyzes the oxidative conversion of Delta5-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. During viral infection, steroid production contributes to virulence by inhibiting the host inflammatory response ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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