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Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1392132

MBS1392132 is a recombinant protein targeting Erap1. Also known as Recombinant Rat Endoplasmic reticulum aminopeptidase 1 (Erap1) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1355 / 0.5 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Endoplasmic reticulum aminopeptidase 1 (Erap1), Recombinant Protein
Full Product Name
Recombinant Rat Endoplasmic reticulum aminopeptidase 1 (Erap1) , partial
Product Gene Name
Product Synonym Gene Name
Erap1
Sequence
LCVQRAERYF REWKASNGNM SLPIDVTLAV FAVGAQNTEG WDFLYSKYQS SLSSTEKSQI EFSLCISQDP EKLQWLLDQS FKGEIIKTQE FPHILTLIGR NPVGYPLAWK FLKENWNKIV QKFELGSSSI AHMVMGTTNQ FSTRARLEEV KGFFSSLKKN GSQLRCVQQT IETIEENIRW MDKNFDKIRL WLQKERQELL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
100,730 Da
Sequence Positions
731-930,Fragment at the C-terminal.
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9JJ22
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Erap1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Erap1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
endoplasmic reticulum aminopeptidase 1
NCBI Official Synonym Full Names
endoplasmic reticulum aminopeptidase 1
NCBI Official Symbol
Erap1
NCBI Official Synonym Symbols
Arts1; Appils
UniProt Protein Name
Endoplasmic reticulum aminopeptidase 1
UniProt Synonym Protein Names
ARTS-1; Adipocyte-derived leucine aminopeptidase; A-LAP; Aminopeptidase PILS; Puromycin-insensitive leucyl-specific aminopeptidase; PILS-AP
UniProt Gene Name
Erap1
UniProt Synonym Gene Names
Appils; Arts1; A-LAP; PILS-AP
NCBI Protein Information
endoplasmic reticulum aminopeptidase 1

NCBI Summary for Erap1

aminopeptidase enzyme; catalyzes the puromycin-insensitive Zn-dependent hydrolysis of N-terminal Leu; plays a role in processing antigenic precursors for MHC class I presentation [RGD, Feb 2006]

UniProt Comments for Erap1

Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Erap1 recombinant protein

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