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All-Trans-Retinol 13,14-Reductase (RETSAT) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1397144

MBS1397144 is a recombinant protein targeting Retsat. Also known as Recombinant Mouse All-trans-retinol 13,14-reductase (Retsat). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1375 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
All-trans-retinol 13,14-reductase (Retsat), Recombinant Protein
Full Product Name
Recombinant Mouse All-trans-retinol 13,14-reductase (Retsat)
Product Gene Name
Retsat recombinant protein
Product Synonym Gene Name
Retsat
Sequence
ASSPNPFAED VKRPPEPLVT DKEARKKVLK QAFSVSRVPE KLDAVVIGSG IGGLASAAVL AKAGKRVLVL EQHTKAGGCC HTFGENGLEF DTGIHYIGRM REGNIGRFIL DQITEGQLDW APMASPFDLM ILEGPNGRKE FPMYSGRKEY IQGLKKKFPK EEAVIDKYME LVKVVARGVS HAVLLKFLPL PLTQLLSKFG LLTRFSPFCR ASTQSLAEVL QQLGASRELQ AVLSYIFPTY GVTPSHTAFS LHALLVDHYI QGAYYPRGGS SEIAFHTIPL IQRAGGAVLT RATVQSVLLD SAGRACGVSV KKGQELVNIY CPVVISNAGM FNTYQHLLPE TVRHLPDVKK QLAMVRPGLS MLSIFICLKG TKEDLKLQST NYYVYFDTDM DKAMERYVSM PKEKAPEHIP LLFIAFPSSK DPTWEERFPD RSTMTALVPM AFEWFEEWQE EPKGKRGVDY ETLKNAFVEA SMSVIMKLFP QLEGKVESVT GGSPLTNQYY LAAPRGATYG ADHDLARLHP HAMASIRAQT PIPNLYLTGQ DIFTCGLMGA LQGALLCSSA ILKRNLYSDL QALGSKVKAQ KKKM
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
67,334 Da
Sequence Positions
26-609, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q64FW2
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Retsat recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Retsat. It may not necessarily be applicable to this product.

NCBI GI #
52627143
NCBI GeneID
67442
NCBI Accession #
NP_080435.3
UniProt Primary Accession #
Q64FW2
UniProt Secondary Accession #
Q149J8; Q3UNN9; Q78JX8; Q8VHE7; Q9CW85
UniProt Related Accession #
Q64FW2
GenBank Nucleotide #
NM_026159.4
NCBI Official Full Name
all-trans-retinol 13,14-reductase
NCBI Official Synonym Full Names
retinol saturase (all trans retinol 13,14 reductase)
NCBI Official Symbol
Retsat
NCBI Official Synonym Symbols
MMT-7; Ppsig; C80029; 0610039N19Rik
UniProt Protein Name
All-trans-retinol 13,14-reductase
UniProt Synonym Protein Names
All-trans-13,14-dihydroretinol saturase; RetSat; PPAR-alpha-regulated and starvation-induced gene protein
Protein Family
All-trans-retinol 13,14-reductase
UniProt Gene Name
Retsat
UniProt Synonym Gene Names
Ppsig; RetSat
NCBI Protein Information
all-trans-retinol 13,14-reductase

UniProt Comments for Retsat

Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol (PubMed:19940255). Does not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A (PubMed:15358783). Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP (PubMed:28855500). Required for adipocyte differentiation in a 3T3-L1 cell culture model (PubMed:19139408). This effect seems not to mimic the in vivo situation in which animals show increased adiposity in the absence of RETSAT (PubMed:19940255).
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Research Articles on Retsat

1. Retsat modulates lipid metabolism and the production of reactive oxygen species.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Retsat recombinant protein

 Products by Pathway  Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram

Diseases associated with Retsat recombinant protein

 Disease Name  Pubmed Publications
 Diabetes Mellitus Antibodies  >1 publications with Retsat and Diabetes Mellitus
 Weight Gain Antibodies  >1 publications with Retsat and Weight Gain
 Disease Models, Animal Antibodies  >1 publications with Retsat and Disease Models, Animal
 Obesity Antibodies  >1 publications with Retsat and Obesity
 Fatty Liver Antibodies  >1 publications with Retsat and Fatty Liver

Organs/Tissues associated with Retsat recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with Retsat and Liver
 Adipose Tissue Antibodies  >3 publications with Retsat and Adipose Tissue
 Intestine Antibodies  >2 publications with Retsat and Intestine
 Connective Tissue Antibodies  >1 publications with Retsat and Connective Tissue
 Kidney Antibodies  >1 publications with Retsat and Kidney
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