Human MNT Recombinant Protein – Cat# MBS1399083

Max-Binding Protein MNT (MNT) Human Recombinant Protein

Name: MNT Recombinant Protein; Max-Binding Protein MNT; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1399083
Price: 1375 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1399083

The MycMaxMad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the MycMaxMad network. This protein has a basic-Helix-Loop-Helix-zipper… More details

$1375 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Max-binding protein MNT (MNT), Recombinant Protein

Full Product Name

Recombinant Human Max-binding protein MNT (MNT)

Product Gene Name

MNT recombinant protein

Product Synonym Gene Name

MNT

Sequence

SIETLLEAAR FLEWQAQQQQ RAREEQERLR LEQEREQEQK KANSLARLAH TLPVEEPRME APPLPLSPPA PPPAPPPPLA TPAPLTVIPI PVVTNSPQPL PPPPPLPAAA QPLPLAPRQP ALVGAPGLSI KEPAPLPSRP QVPTPAPLLP DSKATIPPNG SPKPLQPLPT PVLTIAPHPG VQPQLAPQQP PPPTLGTLKL APAEEVKSSE QKKRPGGIGT REVHNKLEKN RRAHLKECFE TLKRNIPNVD DKKTSNLSVL RTALRYIQSL KRKEKEYEHE MERLAREKIA TQQRLAELKH ELSQWMDVLE IDRVLRQTGQ PEDDQASTST ASEGEDNIDE DMEEDRAGLG PPKLSHRPQP ELLKSTLPPP STTPAPLPPH PHPHPHSVAL PPAHLPVQQQ QPQQKTPLPA PPPPPAAPAQ TLVPAPAHLV ATAGGGSTVI AHTATTHASV IQTVNHVLQG PGGKHIAHIA PSAPSPAVQL APATPPIGHI TVHPATLNHV AHLGSQLPLY PQPVAVSHIA HTLSHQQVNG TAGLGPPATV MAKPAVGAQV VHHPQLVGQT VLNPVTMVTM PSFPVSTLKL A

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

62,300 Da

Sequence Positions

2-582, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

603039

3D Structure

ModBase 3D Structure for Q99583

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MNT recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MNT purchase

MBS1399083 is a recombinant protein targeting MNT. Also known as Recombinant Human Max-binding protein MNT (MNT). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for MNT. It may not necessarily be applicable to this product.

NCBI GI #

9945318

NCBI GeneID

4335

NCBI Accession #

NP_064706.1

UniProt Primary Accession #

Q99583

UniProt Secondary Accession #

Q1ED38; A8K6D1; D3DTI7

UniProt Related Accession #

Q99583

GenBank Nucleotide #

NM_020310.2

NCBI Official Full Name

max-binding protein MNT

NCBI Official Synonym Full Names

MAX network transcriptional repressor

NCBI Official Symbol

MNT

NCBI Official Synonym Symbols

ROX; MAD6; MXD6; bHLHd3

UniProt Protein Name

Max-binding protein MNT

UniProt Synonym Protein Names

Class D basic helix-loop-helix protein 3; bHLHd3; Myc antagonist MNT; Protein ROX

Protein Family

Max-binding protein

UniProt Gene Name

MNT

UniProt Synonym Gene Names

BHLHD3; ROX; bHLHd3

NCBI Protein Information

max-binding protein MNT

NCBI Summary for MNT

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]

UniProt Comments for MNT

Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.

Research Articles on MNT

1. In vitro, uremia induced dysregulation of DNA methylation in differentiating monocytes, which affected several transcription regulators important for monocyte differentiation (e.g., FLT3, HDAC1, MNT) and led to enhanced generation of intermediate monocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MNT recombinant protein

Reference Product	PubMed Publications
MAX recombinant protein	>71 publications with MNT and MAX
MLX recombinant protein	>4 publications with MNT and MLX
SIN3A recombinant protein	>1 publications with MNT and SIN3A

Diseases associated with MNT recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>87 publications with MNT and Neoplasms
Drug Toxicity Antibodies	>64 publications with MNT and Drug Toxicity
Nervous System Diseases Antibodies	>26 publications with MNT and Nervous System Diseases
Immune System Diseases Antibodies	>26 publications with MNT and Immune System Diseases
Carcinoma Antibodies	>25 publications with MNT and Carcinoma
Cardiovascular Diseases Antibodies	>23 publications with MNT and Cardiovascular Diseases
Adenocarcinoma Antibodies	>15 publications with MNT and Adenocarcinoma
Breast Neoplasms Antibodies	>14 publications with MNT and Breast Neoplasms
Liver Diseases Antibodies	>11 publications with MNT and Liver Diseases
Inflammation Antibodies	>10 publications with MNT and Inflammation

Organs/Tissues associated with MNT recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>142 publications with MNT and Blood
Bone Antibodies	>35 publications with MNT and Bone
Bone Marrow Antibodies	>27 publications with MNT and Bone Marrow
Brain Antibodies	>21 publications with MNT and Brain
Nerve Antibodies	>20 publications with MNT and Nerve
Kidney Antibodies	>17 publications with MNT and Kidney
Skin Antibodies	>13 publications with MNT and Skin
Mouth Antibodies	>8 publications with MNT and Mouth
Lung Antibodies	>6 publications with MNT and Lung
Eye Antibodies	>6 publications with MNT and Eye