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Estradiol 17-Beta-Dehydrogenase 8 (HSD17B8) Pig Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1399574

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone.… More details

$940 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Estradiol 17-beta-dehydrogenase 8 (HSD17B8), Recombinant Protein
Full Product Name
Recombinant Pig Estradiol 17-beta-dehydrogenase 8 (HSD17B8)
Product Synonym Gene Name
HSD17B8
Sequence
MASQLRLRSA LALVTGAGSG IGRAVSVRLA AEGAAVAACD LDGAAAQETV QLLGGPGSEK GAPSGPMAAF QADVSEAETA RRLLEQVQAY FFRPPSVVVS CAGITRDEFL LRMSEDDWDK VIAVNLKGIF LVTQAAAQAL VSSGCPGSII NISSIIGKVG NMGQTNYAAS KAGVIGLTQA VARELGRYRI RCNSVLPGFI KTPMAQKVPQ KVLDKVVGMI PMGHLGGPPD VADVVAFLAS EDSGYITGAS VEVTGGLFM
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
26,622 Da
Sequence Positions
1-259, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9XT00
Species
Sus scrofa (Pig)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HSD17B8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HSD17B8 purchase

MBS1399574 is a recombinant protein targeting HSD17B8. Also known as Recombinant Pig Estradiol 17-beta-dehydrogenase 8 (HSD17B8). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for HSD17B8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Estradiol 17-beta-dehydrogenase 8
NCBI Official Symbol
HSD17B8
NCBI Official Synonym Symbols
KE6; HKE6; Ke-6; FABGL
UniProt Protein Name
Estradiol 17-beta-dehydrogenase 8
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit
UniProt Gene Name
HSD17B8
UniProt Synonym Gene Names
FABGL; HKE6; Ke-6
NCBI Protein Information
estradiol 17-beta-dehydrogenase 8

UniProt Comments for HSD17B8

NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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