Human CA12 Active Protein – Cat# MBS140702

Carbonic Anhydrase XII (CA12) Human Active Protein

Name: CA12 Active Protein; Carbonic Anhydrase XII; Human; MyBioSource
Brand: MyBioSource
SKU: MBS140702
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140702

Introduction: Carbonic anhydrase 12 (CA12) is an enzyme that belongs to the Carbonic anhydrases (CAs) family. This is a large family of zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. They are involved in various biological… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Carbonic Anhydrase XII (CA12), Active Protein

Full Product Name

Recombinant Human Carbonic Anhydrase XII

Product Gene Name

CA12 active protein

Product Synonym Names

CA12 Human; Carbonic Anhydrase XII Human Recombinant; Carbonic anhydrase 12; Carbonate dehydratase XII; Carbonic anhydrase XII; CA-XII; Tumor antigen HOM-RCC-3.1.3; CA12; Carbonic Anhydrase XII; Carbonic anhydrase 12 isoform 1; CAXII; HsT18816

Sequence

APVNGSKWTY FGPDGENSWS KKYPSCGGLL QSPIDLHSDI LQYDASLTPL EFQGYNLSAN KQFLLTNNGH SVKLNLPSDM HIQGLQSRYS ATQLHLHWGN PNDPHGSEHT VSGQHFAAEL HIVHYNSDLY PDASTASNKS EGLAVLAVLI EMGSFNPSYD KIFSHLQHVK YKGQEAFVPG FNIEELLPER TAEYYRYRGS LTTPPCNPTV LWTVFRNPVQ ISQEQLLALE TALYCTHMDD PSPREMINNF RQVQKFDERL VYTSFSQVQV CTAAGLS HHH HHH.

Host

Sf9 Baculovirus Cells

Form/Format

CA12 protein solution (0.5mg/ml) containing Phosphate Buffer Saline (pH7.4) and 10% glycerol.
Sterile Filtered clear solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

OMIM

143860

3D Structure

ModBase 3D Structure for O43570

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Specific activity is > 300 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1.0 pmole of 4-nitrophenyl acetate to 4-nitrophenol per minute at pH 7.5 at 37°C.

Product Categories/Family for CA12 active protein

Enzymes

Other Notes

Small volumes of CA12 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CA12 purchase

MBS140702 is an active protein targeting CA12. Also known as Recombinant Human Carbonic Anhydrase XII. Host: Sf9 Baculovirus Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for CA12. It may not necessarily be applicable to this product.

NCBI GI #

4502515

NCBI GeneID

771

NCBI Accession #

NP_001209.1

UniProt Primary Accession #

O43570

UniProt Secondary Accession #

Q53YE5; Q9BWG2; B2RE24

UniProt Related Accession #

O43570

GenBank Nucleotide #

NM_001218.4

NCBI Official Full Name

carbonic anhydrase 12 isoform 1

NCBI Official Synonym Full Names

carbonic anhydrase 12

NCBI Official Symbol

CA12

NCBI Official Synonym Symbols

CAXII; CA-XII; T18816; HsT18816

UniProt Protein Name

Carbonic anhydrase 12

UniProt Synonym Protein Names

Carbonate dehydratase XII; Carbonic anhydrase XII; CA-XII; Tumor antigen HOM-RCC-3.1.3

Protein Family

Carbonic anhydrase

UniProt Gene Name

CA12

UniProt Synonym Gene Names

CA-XII

UniProt Entry Name

CAH12_HUMAN

NCBI Protein Information

carbonic anhydrase 12

UniProt Comments for CA12

Reversible hydration of carbon dioxide.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CA12 active protein

Products by Pathway	Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Nitrogen Metabolism Pathway antibodies	Nitrogen Metabolism Pathway Diagram
Nitrogen Metabolism Pathway antibodies	Nitrogen Metabolism Pathway Diagram
Reversible Hydration Of Carbon Dioxide Pathway antibodies	Reversible Hydration Of Carbon Dioxide Pathway Diagram

Diseases associated with CA12 active protein

Disease Name	Pubmed Publications
Adenocarcinoma Antibodies	>18 publications with CA12 and Adenocarcinoma
Breast Neoplasms Antibodies	>15 publications with CA12 and Breast Neoplasms
Kidney Diseases Antibodies	>9 publications with CA12 and Kidney Diseases
Ovarian Neoplasms Antibodies	>7 publications with CA12 and Ovarian Neoplasms
Uterine Cervical Neoplasms Antibodies	>5 publications with CA12 and Uterine Cervical Neoplasms
Nervous System Diseases Antibodies	>5 publications with CA12 and Nervous System Diseases
Fibrosis Antibodies	>4 publications with CA12 and Fibrosis
Neoplasm Metastasis Antibodies	>4 publications with CA12 and Neoplasm Metastasis
Necrosis Antibodies	>4 publications with CA12 and Necrosis
Liver Diseases Antibodies	>4 publications with CA12 and Liver Diseases

Organs/Tissues associated with CA12 active protein

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>11 publications with CA12 and Kidney
Bone Antibodies	>10 publications with CA12 and Bone
Mouth Antibodies	>7 publications with CA12 and Mouth
Lung Antibodies	>6 publications with CA12 and Lung
Liver Antibodies	>6 publications with CA12 and Liver
Vascular Antibodies	>6 publications with CA12 and Vascular
Eye Antibodies	>5 publications with CA12 and Eye
Ascites Antibodies	>4 publications with CA12 and Ascites
Thyroid Antibodies	>4 publications with CA12 and Thyroid
Brain Antibodies	>4 publications with CA12 and Brain