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CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140873

Introduction: CAMP Responsive Element Binding Protein 3-Like 2, also known as CREB3L2 belongs to the oasis bZIP transcription factor family. Members of this family are able to dimerize however from homodimers only. CREB3L2 is a transcriptional activator.… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CAMP Responsive Element Binding Protein 3-Like 2 (CREB3L2), Recombinant Protein
Full Product Name
Recombinant Human CAMP Responsive Element Binding Protein 3-Like 2
Product Gene Name
CREB3L2 recombinant protein
Product Synonym Names
CREB3L2 Human; CAMP Responsive Element Binding Protein 3-Like 2 Human Recombinant; CAMP Responsive Element Binding Protein 3-Like 2; BBF2H7; CAMP-Responsive Element-Binding Protein 3-Like Protein 2; BBF2 Human Homolog On Chromosome 7; Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 2; Basic Transcription Factor 2; B-ZIB Transcription Factor; FUS/BBF2H7 Protein; TCAG_1951439; Cyclic AMP-responsive element-binding protein 3-like protein 2; cAMP-responsive element-binding protein 3-like protein 2
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMEV LESG EQGVLQWDRK LSELSEPGDG EALMYHTHFS ELLDEFSQNV LGQLLNDPFL SEKSVSMEVE PSPTSPAPLI QAEHSYSLCE EPRAQSPFTH ITSDSFNDDE VESEKWYLST DFPSTSIKTE PITDEPPPGL VPSVTLTITA ISTPLEKEEP PLEMNTGVDS SCQTIIPKIK LEPHEVDQFL NFSPKEAPVD HLHLPPTPPS SHGSDSEGSL SPNPRLHPFS LPQTHSPSRA APRAPSALSS SPLLTAPHKL QGSGPLVLTE EEKRTLIAEG YPIPTKLPLS KSEEKALKKI RRKIKNKISA QESRRKKKEY MDSLEKKVES CSTENLELRK KVEVLENTNR TLLQQLQKLQ TLVMGKVSRT CKLAGTQTGT C
Host
E Coli
Form/Format
CREB3L2 protein solution (0.25mg/ml) containing PBS (pH 7.4), 30% glycerol and 1mM DTT.
Sterile filtered colorless solution.
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Molecular Weight
27,722 Da
OMIM
608834
3D Structure
ModBase 3D Structure for Q70SY1

Product Categories/Family for CREB3L2 recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of CREB3L2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CREB3L2 purchase

MBS140873 is a recombinant protein targeting CREB3L2. Also known as Recombinant Human CAMP Responsive Element Binding Protein 3-Like 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CREB3L2. It may not necessarily be applicable to this product.

NCBI GI #
359339005
NCBI GeneID
64764
NCBI Accession #
NP_001240704.1
UniProt Primary Accession #
Q70SY1
UniProt Secondary Accession #
Q6P454; Q6ZMR6
UniProt Related Accession #
Q70SY1
GenBank Nucleotide #
NM_001253775.1
NCBI Official Full Name
cyclic AMP-responsive element-binding protein 3-like protein 2 isoform 2
NCBI Official Synonym Full Names
cAMP responsive element binding protein 3-like 2
NCBI Official Symbol
CREB3L2
NCBI Official Synonym Symbols
BBF2H7
UniProt Protein Name
Cyclic AMP-responsive element-binding protein 3-like protein 2
UniProt Synonym Protein Names
BBF2 human homolog on chromosome 7
Protein Family
Cyclic AMP-responsive element-binding protein 3-like protein
UniProt Gene Name
CREB3L2
UniProt Synonym Gene Names
BBF2H7; cAMP-responsive element-binding protein 3-like protein 2
UniProt Entry Name
CR3L2_HUMAN
NCBI Protein Information
cyclic AMP-responsive element-binding protein 3-like protein 2

UniProt Comments for CREB3L2

CREB3L2: Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage. A chromosomal aberration involving CREB3L2 is found in low grade fibromyxoid sarcoma (LGFMS). Translocation t(7;16)(q33;p11) with FUS. Belongs to the bZIP family. ATF subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Oncoprotein; Transcription factor

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: endoplasmic reticulum; nucleoplasm; nucleus

Biological Process: cartilage development; chondrocyte differentiation; positive regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CREB3L2 recombinant protein

 Reference Product  PubMed Publications
 ATF5 recombinant protein  >3 publications with CREB3L2 and ATF5
 MCL1 recombinant protein  >2 publications with CREB3L2 and MCL1

Pathways associated with CREB3L2 recombinant protein

 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
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 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
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 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram

Diseases associated with CREB3L2 recombinant protein

 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >3 publications with CREB3L2 and Fibrosis
 Skin Neoplasms Antibodies  >2 publications with CREB3L2 and Skin Neoplasms
 Adenocarcinoma Antibodies  >2 publications with CREB3L2 and Adenocarcinoma
 Neoplasm Metastasis Antibodies  >2 publications with CREB3L2 and Neoplasm Metastasis
 Heart Diseases Antibodies  >1 publications with CREB3L2 and Heart Diseases
 Neoplasms, Experimental Antibodies  >1 publications with CREB3L2 and Neoplasms, Experimental
 Vascular Diseases Antibodies  >1 publications with CREB3L2 and Vascular Diseases
 Kidney Diseases Antibodies  >1 publications with CREB3L2 and Kidney Diseases
 Necrosis Antibodies  >1 publications with CREB3L2 and Necrosis

Organs/Tissues associated with CREB3L2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >20 publications with CREB3L2 and Nerve
 Bone Antibodies  >12 publications with CREB3L2 and Bone
 Muscle Antibodies  >5 publications with CREB3L2 and Muscle
 Brain Antibodies  >4 publications with CREB3L2 and Brain
 Connective Tissue Antibodies  >3 publications with CREB3L2 and Connective Tissue
 Skin Antibodies  >3 publications with CREB3L2 and Skin
 Thyroid Antibodies  >2 publications with CREB3L2 and Thyroid
 Blood Antibodies  >2 publications with CREB3L2 and Blood
 Lung Antibodies  >2 publications with CREB3L2 and Lung
 Embryonic Tissue Antibodies  >2 publications with CREB3L2 and Embryonic Tissue
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