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3-Hydroxy-3-Methylglutaryl-Coa Synthase 1 (HMGCS1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140921

Introduction: 3-Hydroxy-3-Methylglutaryl-CoA Synthase 1, also known as HMGCS1 is a member of the Belongs to the HMG-CoA synthase family. HMGCS1 condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (HMGCS1), Recombinant Protein
Full Product Name
Recombinant Human 3-Hydroxy-3-Methylglutaryl-CoA Synthase 1
Product Synonym Names
HMGCS1 Human; 3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 Human Recombinant; 3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble); 3-Hydroxy-3-Methylglutaryl-Coenzyme A Synthase 1 (Soluble); 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Synthase; EC 2.3.3.10; HMGCS; Hydroxymethylglutaryl-CoA Synthase; Cytoplasmic; 3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase; HMG-CoA Synthase
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMPG SLPL NAEACWPKDV GIVALEIYFP SQYVDQAELE KYDGVDAGKY TIGLGQAKMG FCTDREDINS LCMTVVQNLM ERNNLSYDCI GRLEVGTETI IDKSKSVKTN LMQLFEESGN TDIEGIDTTN ACYGGTAAVF NAVNWIESSS WDGRYALVVA GDIAVYATGN ARPTGGVGAV ALLIGPNAPL IFERGLRGTH MQHAYDFYKP DMLSEYPIVD GKLSIQCYLS ALDRCYSVYC KKIHAQWQKE GNDKDFTLND FGFMIFHSPY CKLVQKSLAR MLLNDFLNDQ NRDKNSIYSG LEAFGDVKLE DTYFDRDVEK AFMKASSELF SQKTKASLLV SNQNGNMYTS SVYGSLASVL AQYSPQQLAG KRIGVFSYGS GLAATLYSLK VTQDATPGSA LDKITASLCD LKSRLDSRTG VAPDVFAENM KLREDTHHLV NYIPQGSIDS LFEGTWYLVR VDEKHRRTYA RRPTPNDDTL DEGVGLVHSN IATEHIPSPA KKVPRLPATA AEPEAAVISN GEH
Host
E Coli
Form/Format
HMGCS1 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT.
Sterile Filtered clear solution.
Purity/Purification
Greater than 80.0% as determined by SDS-PAGE.
Molecular Weight
57,294 Da
OMIM
142940
3D Structure
ModBase 3D Structure for Q01581

Product Categories/Family for HMGCS1 recombinant protein

Other Notes

Small volumes of HMGCS1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HMGCS1 purchase

MBS140921 is a recombinant protein targeting HMGCS1. Also known as Recombinant Human 3-Hydroxy-3-Methylglutaryl-CoA Synthase 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for HMGCS1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
hydroxymethylglutaryl-CoA synthase, cytoplasmic
NCBI Official Synonym Full Names
3-hydroxy-3-methylglutaryl-CoA synthase 1
NCBI Official Symbol
HMGCS1
NCBI Official Synonym Symbols
HMGCS
UniProt Protein Name
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
UniProt Synonym Protein Names
3-hydroxy-3-methylglutaryl coenzyme A synthase
UniProt Gene Name
HMGCS1
UniProt Synonym Gene Names
HMGCS; HMG-CoA synthase
UniProt Entry Name
HMCS1_HUMAN
NCBI Protein Information
hydroxymethylglutaryl-CoA synthase, cytoplasmic

UniProt Comments for HMGCS1

HMGCS1: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Belongs to the HMG-CoA synthase family.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - butanoate; EC 2.3.3.10; Lipid Metabolism - synthesis and degradation of ketone bodies; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Transferase

Chromosomal Location of Human Ortholog: 5p14-p13

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus; plasma membrane

Molecular Function: hydroxymethylglutaryl-CoA synthase activity

Biological Process: cholesterol biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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