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Bone Marrow Stromal Cell Antigen 1 (BST1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS141235

Description: BST1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 267 amino acids (33-293a.a.) and having a molecular mass of 30.5kDa. (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).BST1 is… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Bone Marrow Stromal Cell Antigen 1 (BST1), Recombinant Protein
Full Product Name
Recombinant Human Bone Marrow Stromal Cell Antigen 1
Product Gene Name
BST1 recombinant protein
Product Synonym Names
Bone Marrow Stromal Cell Antigen 1 Human Recombinant; Bone Marrow Stromal Cell Antigen 1; ADP-Ribosyl Cyclase 2; Bone Marrow Stromal Antigen 1; Cyclic ADP-Ribose Hydrolase 2; NAD(+) Nucleosidase; CADPr Hydrolase 2; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2; CD157 Antigen; EC 3.2.2.6; CD157; BST-1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; BST1 Human
Sequence
RWRGEGTSAH LRDIFLGRCA EYRALLSPEQ RNKNCTAIWE AFKVALDKDP CSVLPSDYDL FINLSRHSIP RDKSLFWENS HLLVNSFADN TRRFMPLSDV LYGRVADFLS WCRQKNDSGL DYQSCPTSED CENNPVDSFW KRASIQYSKD SSGVIHVMLN GSEPTGAYPI KGFFADYEIP NLQKEKITRI EIWVMHEIGG PNVESCGEGS MKVLEKRLKD MGFQYSCIND YRPVKLLQCV DHSTHPDCAL KSAAAATQRK AHHHHHH.
Host
Sf9, Baculovirus cells
Form/Format
Sterile filtered colorless solution.
Protein solution (0.5mg/ml) contains 10% glycerol & Phosphate Buffered Saline (pH 7.4).
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Molecular Weight
29,326 Da
3D Structure
ModBase 3D Structure for Q10588

Product Categories/Family for BST1 recombinant protein

Cytokines and Growth Factors

Other Notes

Small volumes of BST1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BST1 purchase

MBS141235 is a recombinant protein targeting BST1. Also known as Recombinant Human Bone Marrow Stromal Cell Antigen 1. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for BST1. It may not necessarily be applicable to this product.

NCBI GI #
116241273
NCBI GeneID
683
NCBI Accession #
Q10588.2
UniProt Primary Accession #
Q10588
UniProt Secondary Accession #
Q1XII0; Q5U0K0; Q96EN3; B2R6A2
UniProt Related Accession #
Q10588
NCBI Official Full Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
NCBI Official Synonym Full Names
bone marrow stromal cell antigen 1
NCBI Official Symbol
BST1
NCBI Official Synonym Symbols
CD157
UniProt Protein Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
UniProt Synonym Protein Names
ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD_antigen: CD157
Protein Family
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
UniProt Gene Name
BST1
UniProt Synonym Gene Names
BST-1; cADPr hydrolase 2
NCBI Protein Information
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2

NCBI Summary for BST1

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
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UniProt Comments for BST1

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.

Research Articles on BST1

1. SNPs rs28532698 and rs4301112 in CD157 are not significantly associated with childhood autism spectrum disorder or the severity of the disease in a Chinese Han population.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with BST1 recombinant protein

 Reference Product  PubMed Publications
 CD38 recombinant protein  >5 publications with BST1 and CD38

Pathways associated with BST1 recombinant protein

 Products by Pathway  Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies  Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
 NAD+ Biosynthetic Pathways antibodies  NAD+ Biosynthetic Pathways Diagram
 Neutrophil Degranulation Pathway antibodies  Neutrophil Degranulation Pathway Diagram
 Nicotinate And Nicotinamide Metabolism Pathway antibodies  Nicotinate And Nicotinamide Metabolism Pathway Diagram

Diseases associated with BST1 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >26 publications with BST1 and Nervous System Diseases
 Parkinson Disease Antibodies  >25 publications with BST1 and Parkinson Disease
 Cardiovascular Diseases Antibodies  >3 publications with BST1 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >2 publications with BST1 and Disease Models, Animal
 Heart Diseases Antibodies  >1 publications with BST1 and Heart Diseases
 Kidney Diseases Antibodies  >1 publications with BST1 and Kidney Diseases
 Learning Disorders Antibodies  >1 publications with BST1 and Learning Disorders
 Lung Neoplasms Antibodies  >1 publications with BST1 and Lung Neoplasms
 Inflammation Antibodies  >1 publications with BST1 and Inflammation
 Hyperplasia Antibodies  >1 publications with BST1 and Hyperplasia

Organs/Tissues associated with BST1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >14 publications with BST1 and Bone Marrow
 Brain Antibodies  >12 publications with BST1 and Brain
 Blood Antibodies  >6 publications with BST1 and Blood
 Muscle Antibodies  >2 publications with BST1 and Muscle
 Prostate Antibodies  >2 publications with BST1 and Prostate
 Liver Antibodies  >2 publications with BST1 and Liver
 Eye Antibodies  >1 publications with BST1 and Eye
 Intestine Antibodies  >1 publications with BST1 and Intestine
 Kidney Antibodies  >1 publications with BST1 and Kidney
 Lung Antibodies  >1 publications with BST1 and Lung
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