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Adiponectin (ADIPOQ) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1416869

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing… More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Adiponectin (Adipoq), Recombinant Protein
Full Product Name
Recombinant Mouse Adiponectin (Adipoq)
Product Gene Name
Adipoq recombinant protein
Product Synonym Gene Name
Adipoq
Sequence
EDDVTTTEEL APALVPPPKG TCAGWMAGIP GHPGHNGTPG RDGRDGTPGE KGEKGDAGLL GPKGETGDVG MTGAEGPRGF PGTPGRKGEP GEAAYVYRSA FSVGLETRVT VPNVPIRFTK IFYNQQNHYD GSTGKFYCNI PGLYYFSYHI TVYMKDVKVS LFKKDKAVLF TYDQYQEKNV DQASGSVLLH LEVGDQVWLQ VYGDGDHNGL YADNVNDSTF TGFLLYHDTN
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
28.9 kDa
Sequence Positions
18-247aa; Full Length of Mature Protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q60994
Species
Mus musculus (Mouse)
Production Note
Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for Adipoq recombinant protein

Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes.Xu A., Chan K.W., Hoo R.L.C., Wang Y., Tan K.C.B., Zhang J., Chen B., Lam M.C., Tse C., Cooper G.J.S., Lam K.S.L.J. Biol. Chem. 280:18073-18080(2005)

Other Notes

Small volumes of Adipoq recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Adipoq purchase

MBS1416869 is a recombinant protein targeting Adipoq. Also known as Recombinant Mouse Adiponectin (Adipoq). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Adipoq. It may not necessarily be applicable to this product.

NCBI GI #
87252711
NCBI GeneID
11450
NCBI Accession #
NP_033735.3
UniProt Primary Accession #
Q60994
UniProt Secondary Accession #
Q62400; Q6GTX4; Q9DC68
UniProt Related Accession #
Q60994
GenBank Nucleotide #
NM_009605.5
NCBI Official Full Name
adiponectin
NCBI Official Synonym Full Names
adiponectin, C1Q and collagen domain containing
NCBI Official Symbol
Adipoq
NCBI Official Synonym Symbols
Ad; APN; Acdc; apM1; 30kDa; GBP28; adipo; Acrp30
UniProt Protein Name
Adiponectin
UniProt Synonym Protein Names
30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ
Protein Family
Adiponectin
UniProt Gene Name
Adipoq
UniProt Synonym Gene Names
Acdc; Acrp30; Apm1; ACRP30
NCBI Protein Information
adiponectin

UniProt Comments for Adipoq

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
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Research Articles on Adipoq

1. plasma adiponectin and leptin were also decreased in IL 10tm.These findings suggest that frailty observed in this mouse model of chronic inflammation may in part be driven by alterations in fat mass, hormone secretion and energy metabolism

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Adipoq recombinant protein

 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with Adipoq and FLNA

Pathways associated with Adipoq recombinant protein

 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Leptin And Adiponectin Pathway antibodies  Leptin And Adiponectin Pathway Diagram
 Non-alcoholic Fatty Liver Disease (NAFLD) Pathway antibodies  Non-alcoholic Fatty Liver Disease (NAFLD) Pathway Diagram
 Non-alcoholic Fatty Liver Disease (NAFLD) Pathway antibodies  Non-alcoholic Fatty Liver Disease (NAFLD) Pathway Diagram
 PPAR (Peroxisome Proliferator-activated Receptor) Signaling Pathway antibodies  PPAR (Peroxisome Proliferator-activated Receptor) Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram

Diseases associated with Adipoq recombinant protein

 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >641 publications with Adipoq and Insulin Resistance
 Obesity Antibodies  >596 publications with Adipoq and Obesity
 Cardiovascular Diseases Antibodies  >424 publications with Adipoq and Cardiovascular Diseases
 Diabetes Mellitus Antibodies  >383 publications with Adipoq and Diabetes Mellitus
 Inflammation Antibodies  >268 publications with Adipoq and Inflammation
 Diabetes Mellitus, Type 2 Antibodies  >266 publications with Adipoq and Diabetes Mellitus, Type 2
 Necrosis Antibodies  >196 publications with Adipoq and Necrosis
 Heart Diseases Antibodies  >187 publications with Adipoq and Heart Diseases
 Atherosclerosis Antibodies  >166 publications with Adipoq and Atherosclerosis
 Metabolic Syndrome X Antibodies  >153 publications with Adipoq and Metabolic Syndrome X

Organs/Tissues associated with Adipoq recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1162 publications with Adipoq and Blood
 Connective Tissue Antibodies  >299 publications with Adipoq and Connective Tissue
 Heart Antibodies  >162 publications with Adipoq and Heart
 Muscle Antibodies  >143 publications with Adipoq and Muscle
 Kidney Antibodies  >66 publications with Adipoq and Kidney
 Pancreas Antibodies  >24 publications with Adipoq and Pancreas
 Joint Antibodies  >18 publications with Adipoq and Joint
 Embryonic Tissue Antibodies  >16 publications with Adipoq and Embryonic Tissue
 Intestine Antibodies  >12 publications with Adipoq and Intestine
 Skin Antibodies  >11 publications with Adipoq and Skin
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