Ornithine Decarboxylase (ODC) ELISA Kit for Rat

Name: Rat ODC ELISA Kit; Ornithine Decarboxylase; MyBioSource
Brand: MyBioSource
SKU: MBS014226
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS014226

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used to determine the level of ODC (hereafter termed "analyte") in undiluted original Rat serum, plasma or tissue homogenates… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Ornithine Decarboxylase (ODC), ELISA Kit

Full Product Name

Rat Ornithine Decarboxylase ELISA Kit

Product Gene Name

ODC elisa kit

Species Reactivity

Rat

Assay Type

Quantitative Sandwich

Samples

Undiluted original Rat serum, plasma or tissue homogenates samples

Detection Range

0.25ng/ml-8ng/ml

Sensitivity

0.1ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

51,148 Da

Chromosome Location

Chromosome: 2; NC_000002.11 (10580508..10588453, complement). Location: 2p25

OMIM

165640

3D Structure

ModBase 3D Structure for P11926

Other Notes

Small volumes of ODC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ODC purchase

MBS014226 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ornithine Decarboxylase (ODC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ODC. The ELISA analytical biochemical technique of the MBS014226 kit is based on ODC antibody-ODC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ODC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ODC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for ODC. It may not necessarily be applicable to this product.

NCBI GI #

4505489

NCBI GeneID

4953

NCBI Accession #

NP_002530.1

UniProt Primary Accession #

P11926

UniProt Secondary Accession #

Q53TU3; Q6LDS9

UniProt Related Accession #

P11926

GenBank Nucleotide #

NM_002539.1

NCBI Official Full Name

ornithine decarboxylase

NCBI Official Synonym Full Names

ornithine decarboxylase 1

NCBI Official Symbol

ODC1

NCBI Official Synonym Symbols

ODC

UniProt Protein Name

Ornithine decarboxylase

Protein Family

Probable ornithine decarboxylase

UniProt Gene Name

ODC1

UniProt Synonym Gene Names

ODC

UniProt Entry Name

DCOR_HUMAN

NCBI Protein Information

ornithine decarboxylase

NCBI Summary for ODC

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]

UniProt Comments for ODC

ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]

Protein type: EC 4.1.1.17; Other Amino Acids Metabolism - glutathione; Lyase; Amino Acid Metabolism - arginine and proline; Cell cycle regulation

Chromosomal Location of Human Ortholog: 2p25

Cellular Component: cytoplasm; cytosol

Molecular Function: protein homodimerization activity; ornithine decarboxylase activity

Biological Process: response to virus; positive regulation of cell proliferation; regulation of protein catabolic process; kidney development; regulation of amino acid metabolic process; putrescine biosynthetic process from ornithine; polyamine metabolic process

Disease: Colorectal Cancer

Research Articles on ODC

1. Overexpression of antizyme (AZ), an ornithine decarboxylase (ODC) inhibitory protein, suppressed ERalpha expression, suggesting that ODC plays an important role in regulation of ERalpha expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ODC elisa kit

Reference Product	PubMed Publications
SRM elisa kit	>2 publications with ODC and SRM
OAZ2 elisa kit	>1 publications with ODC and OAZ2
SAT1 elisa kit	>1 publications with ODC and SAT1
OAZ1 elisa kit	>1 publications with ODC and OAZ1

Pathways associated with ODC elisa kit

Products by Pathway	Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
Metabolism Of Polyamines Pathway antibodies	Metabolism Of Polyamines Pathway Diagram
Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway antibodies	Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway Diagram
Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway antibodies	Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway Diagram
Regulation Of Ornithine Decarboxylase (ODC) Pathway antibodies	Regulation Of Ornithine Decarboxylase (ODC) Pathway Diagram

Diseases associated with ODC elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>15 publications with ODC and Neoplasms
Colorectal Neoplasms Antibodies	>5 publications with ODC and Colorectal Neoplasms
Drug Toxicity Antibodies	>2 publications with ODC and Drug Toxicity
Neoplasms, Experimental Antibodies	>2 publications with ODC and Neoplasms, Experimental
Colonic Neoplasms Antibodies	>2 publications with ODC and Colonic Neoplasms
Lung Neoplasms Antibodies	>1 publications with ODC and Lung Neoplasms
Breast Neoplasms Antibodies	>1 publications with ODC and Breast Neoplasms
Hypertension Antibodies	>1 publications with ODC and Hypertension
Heart Diseases Antibodies	>1 publications with ODC and Heart Diseases
Necrosis Antibodies	>1 publications with ODC and Necrosis

Organs/Tissues associated with ODC elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>5 publications with ODC and Muscle
Brain Antibodies	>3 publications with ODC and Brain
Liver Antibodies	>2 publications with ODC and Liver
Uterus Antibodies	>2 publications with ODC and Uterus
Embryonic Tissue Antibodies	>2 publications with ODC and Embryonic Tissue
Prostate Antibodies	>2 publications with ODC and Prostate
Lung Antibodies	>2 publications with ODC and Lung
Blood Antibodies	>2 publications with ODC and Blood
Ovary Antibodies	>2 publications with ODC and Ovary
Bone Antibodies	>1 publications with ODC and Bone