Human SUMO4 Recombinant Protein – Cat# MBS1424429

Small Ubiquitin-Related Modifier 4 (SUMO4) Human Recombinant Protein

Name: SUMO4 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1424429
Price: 385 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1424429

MBS1424429 is a recombinant protein targeting SUMO4. Also known as Recombinant Human Small ubiquitin-related modifier 4 (SUMO4). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. Small ubiquitin-like protein 4 More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Small ubiquitin-related modifier 4 (SUMO4), Recombinant Protein

Full Product Name

Recombinant Human Small ubiquitin-related modifier 4 (SUMO4)

Product Gene Name

SUMO4 recombinant protein

Product Synonym Gene Name

SUMO4; SMT3H4

Product Synonym Names

Small ubiquitin-related modifier 4; SUMO-4; Small ubiquitin-like protein 4

Sequence

MANEKPTEEV KTENNNHINL KVAGQDGSVV QFKIKRQTPL SKLMKAYCEP RGLSVKQIRF RFGGQPISGT DKPAQLEMED EDTIDVFQQP TGGVY

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

37.7 kDa

Sequence Positions

1-95aa; Full Length of BC130305

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

608829

3D Structure

ModBase 3D Structure for Q6EEV6

Species

Homo sapiens (Human)

Product Categories/Family for SUMO4 recombinant protein

Cell Biology

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SUMO4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SUMO4. It may not necessarily be applicable to this product.

NCBI GI #

50400081

NCBI GeneID

387082

NCBI Accession #

NP_001002255.1

UniProt Primary Accession #

Q6EEV6

UniProt Secondary Accession #

A1L3W5

UniProt Related Accession #

Q6EEV6

GenBank Nucleotide #

NM_001002255.1

NCBI Official Full Name

small ubiquitin-related modifier 4

NCBI Official Synonym Full Names

small ubiquitin-like modifier 4

NCBI Official Symbol

SUMO4

NCBI Official Synonym Symbols

IDDM5; SMT3H4; SUMO-4; dJ281H8.4

UniProt Protein Name

Small ubiquitin-related modifier 4

UniProt Synonym Protein Names

Small ubiquitin-like protein 4

Protein Family

Putative small ubiquitin-related modifier

UniProt Gene Name

SUMO4

UniProt Synonym Gene Names

SMT3H4; SUMO-4

UniProt Entry Name

SUMO4_HUMAN

NCBI Protein Information

small ubiquitin-related modifier 4; insulin-dependent diabetes mellitus 5; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 4; small ubiquitin-like modifier 4 protein

NCBI Summary for SUMO4

This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq, Jul 2008]

UniProt Comments for SUMO4

SUMO4: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. Belongs to the ubiquitin family. SUMO subfamily.

Protein type: Ubiquitin-like modifier

Chromosomal Location of Human Ortholog: 6q25

Cellular Component: nucleus

Biological Process: protein sumoylation

Disease: Diabetes Mellitus, Insulin-dependent, 5

Research Articles on SUMO4

1. No association between SUMO4 gene polymorphisms and acoronary artery disease with and without type 2 diabetes mellitus.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SUMO4 recombinant protein

Reference Product	PubMed Publications
SUMO1 recombinant protein	>6 publications with SUMO4 and SUMO1

Pathways associated with SUMO4 recombinant protein

Products by Pathway	Pathway Diagram
Nuclear Pore Complex Pathway antibodies	Nuclear Pore Complex Pathway Diagram
Nuclear Pore Complex Pathway antibodies	Nuclear Pore Complex Pathway Diagram
RNA Transport Pathway antibodies	RNA Transport Pathway Diagram
RNA Transport Pathway antibodies	RNA Transport Pathway Diagram

Diseases associated with SUMO4 recombinant protein

Disease Name	Pubmed Publications
Diabetes Mellitus, Insulin-Dependent, 5 Antibodies	>5 publications with SUMO4 and Diabetes Mellitus, Insulin-Dependent, 5
Inflammation Antibodies	>3 publications with SUMO4 and Inflammation
Heart Diseases Antibodies	>2 publications with SUMO4 and Heart Diseases
Necrosis Antibodies	>2 publications with SUMO4 and Necrosis
Adenoma Antibodies	>1 publications with SUMO4 and Adenoma
Pancreatic Neoplasms Antibodies	>1 publications with SUMO4 and Pancreatic Neoplasms
Disease Models, Animal Antibodies	>1 publications with SUMO4 and Disease Models, Animal