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TROVE Domain Family (TROVE2) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS142884

Description: RO-60 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 60kDa.The RO-60 is purified by proprietary chromatographic techniques.Introduction: Ro 60 kDa autoantigen is an RNA-binding… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TROVE Domain Family (TROVE2), Recombinant Protein
Full Product Name
Recombinant Human RO-60 (SS-A) RO-60 Human
Product Synonym Names
TROVE2 Human; TROVE Domain Family Member 2 Human Recombinant; 60 kDa SS-A/Ro ribonucleoprotein; 60 kDa ribonucleoprotein Ro; RoRNP; 60 kDa Ro protein; Ro 60 kDa autoantigen; TROVE domain family member 2; Sjoegren syndrome type A antigen; SS-A; Sjoegren syndrome antigen A2; TROVE2; RO60; SSA2; RO-60
Host
E Coli
Form/Format
The protein solution (0.671mg/ml) contains 6M Urea, 500mM NaCl, 500mM imidazole and 10mM Tris pH-6.
Sterile Filtered clear solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
RO-60 although stable at 4 degree C for 3 weeks, should be stored below -18 degree C. Please prevent freeze-thaw cycles.
Molecular Weight
59,270 Da
OMIM
600063
3D Structure
ModBase 3D Structure for P10155
Protein Content
Protein quantitation was carried out by using 0.5 - 2.0 mg/ml Bradford assay vs. BSA.

Other Notes

Small volumes of TROVE2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TROVE2 purchase

MBS142884 is a recombinant protein targeting TROVE2. Also known as Recombinant Human RO-60 (SS-A) RO-60 Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TROVE2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
60 kDa SS-A/Ro ribonucleoprotein isoform 1
NCBI Official Synonym Full Names
TROVE domain family, member 2
NCBI Official Symbol
TROVE2
NCBI Official Synonym Symbols
RO60; SSA2; RORNP
UniProt Protein Name
60 kDa SS-A/Ro ribonucleoprotein
UniProt Synonym Protein Names
Ro 60 kDa autoantigen; Sjoegren syndrome antigen A2; Sjoegren syndrome type A antigen; SS-A; TROVE domain family member 2
UniProt Gene Name
TROVE2
UniProt Synonym Gene Names
RO60; SSA2; 60 kDa Ro protein; 60 kDa ribonucleoprotein Ro; RoRNP; SS-A
UniProt Entry Name
RO60_HUMAN
NCBI Protein Information
60 kDa SS-A/Ro ribonucleoprotein; 60 kDa ribonucleoprotein Ro; Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-A/Ro); gastric cancer multi-drug resistance protein; sjoegren syndrome type A antigen

UniProt Comments for TROVE2

SSA2: RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation. Belongs to the Ro 60 kDa family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 1q31

Cellular Component: nucleoplasm; cytoplasm; ribonucleoprotein complex

Molecular Function: RNA binding; metal ion binding; U2 snRNA binding

Biological Process: transcription from RNA polymerase III promoter; immune system development; smoothened signaling pathway; response to UV

Disease: Heart Block, Congenital
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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