Human HRASLS3 Recombinant Protein – Cat# MBS143492

HRAS-Like Suppressor 3 (HRASLS3) Human Recombinant Protein

Name: HRASLS3 Recombinant Protein; HRAS-Like Suppressor 3; Human; MyBioSource
Brand: MyBioSource
SKU: MBS143492
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143492

Description: HRASLS3 Human Recombinant amino produced in E Coli is a single, non-glycosylated polypeptide chain containing 133 amino acids (1-133) having a molecular mass of 14.9 kDa. The HRASLS3 is purified by proprietary chromatographic… More details

$250 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HRAS-Like Suppressor 3 (HRASLS3), Recombinant Protein

Full Product Name

Recombinant Human HRAS-Like Suppressor 3 (PLA2G16)

Product Gene Name

HRASLS3 recombinant protein

Product Synonym Names

HRASLS3 Human; HRAS-Like Suppressor 3 Human Recombinant (PLA2G16); PLA2G16; Phospholipase A2 Group XVI; AdPLA; H-REV107-1; HREV107; HREV107-3; MGC118754; HRAS-like suppressor 3; H-rev 107 protein homolog; Renal carcinoma antigen NY-REN-65; HRASLS3

Sequence

MRAPIPEPKP GDLIEIFRPF YRHWAIYVGD GYVVHLAPPS EVAGAGAASV MSALTDKAIV KKELLYDVAG SDKYQVNNKH DDKYSPLPCS KIIQRAEELV GQEVLYKLTS ENCEHFVNEL RYGVARSDQV RDV

Host

E Coli

Form/Format

The protein contains 20mM Tris-HCl buffer pH 8.
Sterile filtered colorless solution.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

17,937 Da

OMIM

613867

3D Structure

ModBase 3D Structure for P53816

Product Categories/Family for HRASLS3 recombinant protein

Enzymes; Secreted Phospholipase A2

Other Notes

Small volumes of HRASLS3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HRASLS3 purchase

MBS143492 is a recombinant protein targeting HRASLS3. Also known as Recombinant Human HRAS-Like Suppressor 3 (PLA2G16). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for HRASLS3. It may not necessarily be applicable to this product.

NCBI GI #

189571621

NCBI GeneID

11145

NCBI Accession #

NP_001121675.1

UniProt Primary Accession #

P53816

UniProt Secondary Accession #

Q3SYI3; Q9HDD1; B2R7Q4; B7XAK5

UniProt Related Accession #

P53816

GenBank Nucleotide #

NM_001128203.1

NCBI Official Full Name

HRAS-like suppressor 3

NCBI Official Synonym Full Names

phospholipase A2, group XVI

NCBI Official Symbol

PLA2G16

NCBI Official Synonym Symbols

AdPLA; HRSL3; HRASLS3; HREV107; HREV107-1; HREV107-3; H-REV107-1

UniProt Protein Name

HRAS-like suppressor 3

UniProt Synonym Protein Names

Adipose-specific phospholipase A2; AdPLA; Group XVI phospholipase A1/A2; H-rev 107 protein homolog; HRAS-like suppressor 1; HREV107-1; HREV107-3; Renal carcinoma antigen NY-REN-65

Protein Family

HRAS-like suppressor

UniProt Gene Name

PLA2G16

UniProt Synonym Gene Names

HRASLS3; HREV107; HRSL3; AdPLA

UniProt Entry Name

HRSL3_HUMAN

NCBI Protein Information

HRAS-like suppressor 3; Ca-independent phospholipase A1/2; H-rev 107 protein homolog; HRAS-like suppressor 1; adipose-specific PLA2; adipose-specific phospholipase A2; group XVI phospholipase A1/A2; group XVI phospholipase A2; renal carcinoma antigen NY-REN-65

UniProt Comments for HRASLS3

PLA2G16: Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue. N- and O- acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity. Belongs to the H-rev107 family.

Protein type: EC 3.1.1.32; EC 3.1.1.4; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.3

Cellular Component: endoplasmic reticulum; perinuclear region of cytoplasm; integral to membrane; cytosol

Molecular Function: phospholipase A2 activity; protein binding; phospholipase A1 activity

Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process; negative regulation of cell cycle

Research Articles on HRASLS3

1. crystal structure of the HRASLS3-LRAT chimeric enzyme in a thioester catalytic intermediate state revealed a major structural rearrangement accompanied by three-dimensional domain swapping dimerization not observed in native HRASLS

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HRASLS3 recombinant protein

Products by Pathway	Pathway Diagram
Acyl Chain Remodelling Of PC Pathway antibodies	Acyl Chain Remodelling Of PC Pathway Diagram
Acyl Chain Remodelling Of PE Pathway antibodies	Acyl Chain Remodelling Of PE Pathway Diagram
Acyl Chain Remodelling Of PI Pathway antibodies	Acyl Chain Remodelling Of PI Pathway Diagram
Acyl Chain Remodelling Of PS Pathway antibodies	Acyl Chain Remodelling Of PS Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Ether Lipid Metabolism Pathway antibodies	Ether Lipid Metabolism Pathway Diagram
Ether Lipid Metabolism Pathway antibodies	Ether Lipid Metabolism Pathway Diagram
Glycerophospholipid Biosynthesis Pathway antibodies	Glycerophospholipid Biosynthesis Pathway Diagram
Glycerophospholipid Metabolism Pathway antibodies	Glycerophospholipid Metabolism Pathway Diagram

Diseases associated with HRASLS3 recombinant protein

Disease Name	Pubmed Publications
Carcinoma Antibodies	>8 publications with HRASLS3 and Carcinoma
Insulin Resistance Antibodies	>2 publications with HRASLS3 and Insulin Resistance
Cell Transformation, Neoplastic Antibodies	>2 publications with HRASLS3 and Cell Transformation, Neoplastic
Neoplasms, Experimental Antibodies	>1 publications with HRASLS3 and Neoplasms, Experimental
Lung Neoplasms Antibodies	>1 publications with HRASLS3 and Lung Neoplasms
Carcinoma, Hepatocellular Antibodies	>1 publications with HRASLS3 and Carcinoma, Hepatocellular
Weight Loss Antibodies	>1 publications with HRASLS3 and Weight Loss
Breast Neoplasms Antibodies	>1 publications with HRASLS3 and Breast Neoplasms
Liver Neoplasms, Experimental Antibodies	>1 publications with HRASLS3 and Liver Neoplasms, Experimental
Liver Neoplasms Antibodies	>1 publications with HRASLS3 and Liver Neoplasms

Organs/Tissues associated with HRASLS3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Adipose Tissue Antibodies	>5 publications with HRASLS3 and Adipose Tissue
Liver Antibodies	>3 publications with HRASLS3 and Liver
Lung Antibodies	>3 publications with HRASLS3 and Lung
Stomach Antibodies	>2 publications with HRASLS3 and Stomach
Kidney Antibodies	>2 publications with HRASLS3 and Kidney
Muscle Antibodies	>2 publications with HRASLS3 and Muscle
Testis Antibodies	>2 publications with HRASLS3 and Testis
Heart Antibodies	>1 publications with HRASLS3 and Heart
Embryonic Tissue Antibodies	>1 publications with HRASLS3 and Embryonic Tissue
Intestine Antibodies	>1 publications with HRASLS3 and Intestine