Mouse CD6 Recombinant Protein – Cat# MBS1441563

T-Cell Differentiation Antigen CD6 (CD6) Mouse Recombinant Protein

Name: CD6 Recombinant Protein; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS1441563
Price: 1570 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1441563

MBS1441563 is a recombinant protein targeting Cd6. Also known as Recombinant Mouse T-cell differentiation antigen CD6 (Cd6), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1570 / 0.5 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

T-cell differentiation antigen CD6 (Cd6), Recombinant Protein

Full Product Name

Recombinant Mouse T-cell differentiation antigen CD6 (Cd6), partial

Product Gene Name

Cd6 recombinant protein

Product Synonym Gene Name

Cd6

Sequence

GLPS PAPSGQHKNG TIPNMTLDLE ERLGIRLVNG SSRCSGSVKV LLESWEPVCA AHWNRAATEA VCKALNCGDS GKVTYLMPPT SELPPGATSG NTSSAGNTTW ARAPTERCRG ANWQFCKVQD QECSSDRRLV WVTCAENQAV RLVDGSSRCA GRVEMLEHGE WGTVCDDTWD LQDAHVVCKQ LKCGWAVKAL AGLHFTPGQG PIHRDQVNCS GTEAYLWDCP GRPGDQYCGH KEDAGVVCSE HQSWRLTGGI DSCEGQVEVY FRGVWSTVCD SEWYPSEAKV LCRSLGCGSA VARPRGLPHS LDGRMYYSCK GQEPALSTCS WRFNNSNLCS QSRAARVVCS GSQRHLNLST SEVPSRVPVT IESSVPVSVK DKDSQGLT

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

67,892 Da

Sequence Positions

17-398

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q61003

Species

Mouse

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Cd6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Cd6. It may not necessarily be applicable to this product.

NCBI GI #

83699412

NCBI GeneID

12511

NCBI Accession #

NP_001032890.1

UniProt Primary Accession #

Q61003

UniProt Secondary Accession #

Q60679; Q61004; Q8BGK1

UniProt Related Accession #

Q61003

GenBank Nucleotide #

NM_001037801.2

NCBI Official Full Name

T-cell differentiation antigen CD6 isoform 1

NCBI Official Synonym Full Names

CD6 antigen

NCBI Official Symbol

Cd6

UniProt Protein Name

T-cell differentiation antigen CD6

UniProt Synonym Protein Names

CD_antigen: CD6

Protein Family

T-cell differentiation antigen

UniProt Gene Name

Cd6

NCBI Protein Information

T-cell differentiation antigen CD6

UniProt Comments for Cd6

Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089). Functions as costimulatory molecule; promotes T-cell activation and proliferation. Contributes to the formation and maturation of the immunological synapse. Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria. LPS binding leads to the activation of signaling cascades and down-stream MAP kinases. Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS.

Research Articles on Cd6

1. these data indicate that CD6 modulates the threshold for thymocyte selection and the generation and/or function of several peripheral T cell subpopulations, including T reg cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Cd6 recombinant protein

Products by Pathway	Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram

Diseases associated with Cd6 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>68 publications with Cd6 and Neoplasms
Inflammation Antibodies	>18 publications with Cd6 and Inflammation
Multiple Sclerosis Antibodies	>15 publications with Cd6 and Multiple Sclerosis
Necrosis Antibodies	>11 publications with Cd6 and Necrosis
Anemia, Hemolytic Antibodies	>11 publications with Cd6 and Anemia, Hemolytic
Carcinoma Antibodies	>10 publications with Cd6 and Carcinoma
Vascular Diseases Antibodies	>7 publications with Cd6 and Vascular Diseases
Lung Diseases Antibodies	>6 publications with Cd6 and Lung Diseases
Adenocarcinoma Antibodies	>5 publications with Cd6 and Adenocarcinoma
Ovarian Diseases Antibodies	>3 publications with Cd6 and Ovarian Diseases

Organs/Tissues associated with Cd6 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>240 publications with Cd6 and Blood
Bone Marrow Antibodies	>67 publications with Cd6 and Bone Marrow
Thymus Antibodies	>26 publications with Cd6 and Thymus
Lymph Node Antibodies	>22 publications with Cd6 and Lymph Node
Skin Antibodies	>17 publications with Cd6 and Skin
Spleen Antibodies	>15 publications with Cd6 and Spleen
Brain Antibodies	>12 publications with Cd6 and Brain
Intestine Antibodies	>12 publications with Cd6 and Intestine
Salivary Gland Antibodies	>3 publications with Cd6 and Salivary Gland
Embryonic Tissue Antibodies	>3 publications with Cd6 and Embryonic Tissue