Human PPIL4 Active Protein – Cat# MBS144167

Peptidylprolyl Isomerase (PPIL4) Human Active Protein

Name: PPIL4 Active Protein; Peptidylprolyl Isomerase; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144167
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144167

Description: PPIL4 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 512 amino acids (1-492 a.a.) and having a molecular mass of 59.4kDa. The PPIL4 is purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Peptidylprolyl Isomerase (PPIL4), Active Protein

Full Product Name

Recombinant Human Peptidylprolyl Isomerase (Cyclophilin)-Like 4

Product Gene Name

PPIL4 active protein

Product Synonym Names

PPIL4 Human; Peptidylprolyl Isomerase (Cyclophilin)-Like 4 Human Recombinant; Peptidyl-prolyl cis-trans isomerase-like 4; PPIase; Cyclophilin-like protein PPIL4; Rotamase PPIL4; PPIL4; HDCME13P

Sequence

MGSSHHH HHH SSGLVPRGSH MAVLLETTLG DVVIDLYTEE RPRACLNFLK LCKIKYYNYC LIHNVQRDFI IQTGDPTGTG RGGESIFGQL YGDQASFFEA EKVPRIKHKK KGTVSMVNNG SDQHGSQFLI TTGENLDYLD GVHTVFGEVT EGMDIIKKIN ETFVDKDFVP YQDIRINHTV ILDDPFDDPP DLLIPDRSPE PTREQLDSGR IGADEEIDDF KGRSAEEVEE IKAEKEAKTQ AILLEMVGDL PDADIKPPEN VLFVCKLNPV TTDEDLEIIF SRFGPIRSCE VIRDWKTGES LCYAFIEFEK EEDCEKAFFK MDNVLIDDRR IHVDFSQSVA KVKWKGKGGK YTKSDFKEYE KEQDKPPNLV LKDKVKPKQD TKYDLILDEQ AEDSKSSHSH TSKKHKKKTH HCSEEKEDED YMPIKNTNQD IYREMGFGHY EEEESCWEKQ KSEKRDRTQN RSRSRSRERD GHYSNSHKSK YQTDLYERER SKKRDRSRSP KKSKDKEKSK YR

Host

E Coli

Form/Format

The PPIL solution (0.5 mg/ml) contains 20mM Tris-HCl buffer(pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 85.0% as determined by SDS-PAGE.

Preparation and Storage

PPIL4 should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Molecular Weight

57,225 Da

OMIM

607609

3D Structure

ModBase 3D Structure for Q8WUA2

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Specific activity is > 190 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 25C in Tris-Hcl pH8.0 using chymotrypsin.

Product Categories/Family for PPIL4 active protein

Enzymes; Cyclophilin

Other Notes

Small volumes of PPIL4 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPIL4 purchase

MBS144167 is an active protein targeting PPIL4. Also known as Recombinant Human Peptidylprolyl Isomerase (Cyclophilin)-Like 4. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PPIL4. It may not necessarily be applicable to this product.

NCBI GI #

20911035

NCBI GeneID

85313

NCBI Accession #

NP_624311.1

UniProt Primary Accession #

Q8WUA2

UniProt Secondary Accession #

Q7Z3Q5; B2RD34

UniProt Related Accession #

Q8WUA2

GenBank Nucleotide #

NM_139126.3

NCBI Official Full Name

peptidyl-prolyl cis-trans isomerase-like 4

NCBI Official Synonym Full Names

peptidylprolyl isomerase (cyclophilin)-like 4

NCBI Official Symbol

PPIL4

NCBI Official Synonym Symbols

HDCME13P

UniProt Protein Name

Peptidyl-prolyl cis-trans isomerase-like 4

UniProt Synonym Protein Names

Cyclophilin-like protein PPIL4; Rotamase PPIL4

Protein Family

Peptidyl-prolyl cis-trans isomerase

UniProt Gene Name

PPIL4

UniProt Synonym Gene Names

PPIase

UniProt Entry Name

PPIL4_HUMAN

NCBI Protein Information

peptidyl-prolyl cis-trans isomerase-like 4; PPIase; cyclophilin-like protein PPIL4; cyclophilin-type peptidyl-prolyl cis-trans isomerase; rotamase PPIL4; serologically defined breast cancer antigen NY-BR-18

NCBI Summary for PPIL4

This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. [provided by RefSeq, Jul 2008]

UniProt Comments for PPIL4

PPIL4: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.

Protein type: Cyclophilin; EC 5.2.1.8; RNA-binding; Isomerase

Chromosomal Location of Human Ortholog: 6q25.1

Cellular Component: nucleus

Molecular Function: peptidyl-prolyl cis-trans isomerase activity; nucleotide binding

Biological Process: protein peptidyl-prolyl isomerization; protein folding

Research Articles on PPIL4

1. Molecular cloning, structure and expression of a novel nuclear RNA-binding cyclophilin-like gene (PPIL4) from human fetal brain

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with PPIL4 active protein

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1 publications with PPIL4 and Kidney
Brain Antibodies	>1 publications with PPIL4 and Brain