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Reticulon 4 Interacting Protein 1 (RTN4IP1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144868

Description: RTN4IP1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 379 amino acids (41-396 a.a.) and having a molecular mass of 41.4kDa. RTN4IP1 is fused to a 24 amino acid His-tag at N-terminus & purified by… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Reticulon 4 Interacting Protein 1 (RTN4IP1), Recombinant Protein
Full Product Name
Recombinant Human Reticulon 4 Interacting Protein 1
Product Synonym Names
RTN4IP1 Human; Reticulon 4 Interacting Protein 1 Human Recombinant; Reticulon-4-interacting protein 1 mitochondrial; NOGO-interacting mitochondrial protein; RTN4IP1; NIMP
Sequence
MGSSHHH HHH SSGLVPRGSH MGSTVM PAWV IDKYGKNEVL RFTQNMMMPI IHYPNEVIVK VHAASVNPID VNMRSGYGAT ALNMKRDPLH VKIKGEEFPL TLGRDVSGVV MECGLDVKYF KPGDEVWAAV PPWKQGTLSE FVVVSGNEVS HKPKSLTHTQ AASLPYVALT AWSAINKVGG LNDKNCTGKR VLILGASGGV GTFAIQVMKA WDAHVTAVCS QDASELVRKL GADDVIDYKS GSVEEQLKSL KPFDFILDNV GGSTETWAPD FLKKWSGATY VTLVTPFLLN MDRLGIADGM LQTGVTVGSK ALKHFWKGVH YRWAFFMASG PCLDDIAELV DAGKIRPVIE QTFPFSKVPE AFLKVERGHA RGKTVINVV.
Host
E Coli
Form/Format
RTN4IP1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Molecular Weight
24,936 Da
OMIM
610502
3D Structure
ModBase 3D Structure for Q8WWV3

Other Notes

Small volumes of RTN4IP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RTN4IP1 purchase

MBS144868 is a recombinant protein targeting RTN4IP1. Also known as Recombinant Human Reticulon 4 Interacting Protein 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RTN4IP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
reticulon-4-interacting protein 1, mitochondrial
NCBI Official Synonym Full Names
reticulon 4 interacting protein 1
NCBI Official Symbol
RTN4IP1
NCBI Official Synonym Symbols
NIMP
UniProt Protein Name
Reticulon-4-interacting protein 1, mitochondrial
UniProt Synonym Protein Names
NOGO-interacting mitochondrial protein
UniProt Gene Name
RTN4IP1
UniProt Synonym Gene Names
NIMP
UniProt Entry Name
RT4I1_HUMAN
NCBI Protein Information
reticulon-4-interacting protein 1, mitochondrial; NOGO-interacting mitochondrial protein

NCBI Summary for RTN4IP1

This gene encodes a novel mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. The interaction of reticulon 4 with mitochondrial proteins may provide insight into the mechanisms for reticulon-induced inhibition of neurite growth. [provided by RefSeq, Jul 2008]
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UniProt Comments for RTN4IP1

RTN4IP1: Appears to be a potent inhibitor of regeneration following spinal cord injury. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: mitochondrion

Molecular Function: zinc ion binding; oxidoreductase activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with RTN4IP1 recombinant protein

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