Human TSSC4 Recombinant Protein – Cat# MBS144995

Tumor Suppressing Subtransferable Candidate 4 (TSSC4) Human Recombinant Protein

Name: TSSC4 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144995
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144995

Description: TSSC4 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 353 amino acids (1-329) and having a molecular mass of 36.8 kDa.TSSC4 is fused to a 24 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Tumor Suppressing Subtransferable Candidate 4 (TSSC4), Recombinant Protein

Full Product Name

Recombinant Human Tumor Suppressing Subtransferable Candidate 4

Product Gene Name

TSSC4 recombinant protein

Product Synonym Names

TSSC4 Human; Tumor Suppressing Subtransferable Candidate 4, Human Recombinant; Tumor suppressing subtransferable candidate 4; Tumor-suppressing STF cDNA 4 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein; protein TSSC4

Sequence

MGSSHHH HHH SSGLVPRGSH MGSHMA EAGT GEPSPSVEGE HGTEYDTLPS DTVSLSDSDS DLSLPGGAEV EALSPMGLPG EEDSGPDEPP SPPSGLLPAT VQPFHLRGMS STFSQRSRDI FDCLEGAARR APSSVAHTSM SDNGGFKRPL APSGRSPVEG LGRAHRSPAS PRVPPVPDYV AHPERWTKYS LEDVTEVSEQ SNQATALAFL GSQSLAAPTD CVSSFNQDPS SCGEGRVIFT KPVRGVEARH ERKRVLGKVG EPGRGGLGNP ATDRGEGPVE LAHLAGPGSP EAEEWGSPHG GLQEVEALSG SVHSGSVPGL PPVETVGFHG SRKRSRDHFR NKSSSPEDPG AEV

Host

E Coli

Form/Format

The TSSC4 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 2mM DTT and 20% glycerol.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90% as determined by SDS-PAGE.

Molecular Weight

27,935 Da

OMIM

603852

3D Structure

ModBase 3D Structure for Q9Y5U2

Product Categories/Family for TSSC4 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of TSSC4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TSSC4 purchase

MBS144995 is a recombinant protein targeting TSSC4. Also known as Recombinant Human Tumor Suppressing Subtransferable Candidate 4. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TSSC4. It may not necessarily be applicable to this product.

NCBI GI #

663071037

NCBI GeneID

10078

NCBI Accession #

NP_001284587.1

UniProt Primary Accession #

Q9Y5U2

UniProt Secondary Accession #

Q86VL2; Q9BRS6; C9JS66

UniProt Related Accession #

Q9Y5U2

GenBank Nucleotide #

NM_001297658.1

NCBI Official Full Name

protein TSSC4 isoform a

NCBI Official Synonym Full Names

tumor suppressing subtransferable candidate 4

NCBI Official Symbol

TSSC4

UniProt Protein Name

Protein TSSC4

UniProt Synonym Protein Names

Tumor-suppressing STF cDNA 4 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein

Protein Family

Protein

UniProt Gene Name

TSSC4

UniProt Entry Name

TSSC4_HUMAN

NCBI Protein Information

protein TSSC4; tumor-suppressing STF cDNA 4 protein; tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein

NCBI Summary for TSSC4

This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

UniProt Comments for TSSC4

TSSC4: This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 11p15.5

Research Articles on TSSC4

1. TSSC4 gene, located in the center of the 11p15 imprinted region, escapes genomic imprinting.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TSSC4 recombinant protein

Reference Product	PubMed Publications
TRPM5 recombinant protein	>2 publications with TSSC4 and TRPM5
TSPAN32 recombinant protein	>2 publications with TSSC4 and TSPAN32
ASCL2 recombinant protein	>1 publications with TSSC4 and ASCL2
PHLDA2 recombinant protein	>1 publications with TSSC4 and PHLDA2
KCNQ1 recombinant protein	>1 publications with TSSC4 and KCNQ1

Diseases associated with TSSC4 recombinant protein

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>1 publications with TSSC4 and Kidney Diseases

Organs/Tissues associated with TSSC4 recombinant protein

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>2 publications with TSSC4 and Embryonic Tissue
Kidney Antibodies	>1 publications with TSSC4 and Kidney
Brain Antibodies	>1 publications with TSSC4 and Brain