Human DECR2 Recombinant Protein – Cat# MBS145258

2,4-Dienoyl Coa Reductase 2 (DECR2) Human Recombinant Protein

Name: DECR2 Recombinant Protein; 2,4-Dienoyl Coa Reductase 2; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145258
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145258

Description: DECR2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 315 amino acids (1-292) and having a molecular mass of 33.2kDa.DECR2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

2,4-Dienoyl CoA Reductase 2 (DECR2), Recombinant Protein

Full Product Name

Recombinant Human 2,4-Dienoyl CoA Reductase 2

Product Gene Name

DECR2 recombinant protein

Product Synonym Names

DECR2 Human; 2,4-Dienoyl CoA Reductase 2 Human Recombinant; Peroxisomal 2; 4-dienoyl-CoA reductase; pDCR; 2; 4-dienoyl-CoA reductase 2; DECR2; PDCR; SDR17C1

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMAQ PPPD VEGDDCLPAY RHLFCPDLLR DKVAFITGGG SGIGFRIAEI FMRHGCHTVI ASRSLPRVLT AARKLAGATG RRCLPLSMDV RAPPAVMAAV DQALKEFGRI DILINCAAGN FLCPAGALSF NAFKTVMDID TSGTFNVSRV LYEKFFRDHG GVIVNITATL GNRGQALQVH AGSAKAAVDA MTRHLAVEWG PQNIRVNSLA PGPISGTEGL RRLGGPQASL STKVTASPLQ RLGNKTEIAH SVLYLASPLA SYVTGAVLVA DGGAWLTFPN GVKGLPDFAS FSAKL.

Host

E Coli

Form/Format

The DECR2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.15M NaCl and 1mM DTT.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Molecular Weight

25,589 Da

OMIM

615839

3D Structure

ModBase 3D Structure for Q9NUI1

Product Categories/Family for DECR2 recombinant protein

Enzymes; Reductase

Other Notes

Small volumes of DECR2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DECR2 purchase

MBS145258 is a recombinant protein targeting DECR2. Also known as Recombinant Human 2,4-Dienoyl CoA Reductase 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for DECR2. It may not necessarily be applicable to this product.

NCBI GI #

10190704

NCBI GeneID

26063

NCBI Accession #

NP_065715.1

UniProt Primary Accession #

Q9NUI1

UniProt Secondary Accession #

Q6ZRS7; Q96ET0

UniProt Related Accession #

Q9NUI1

GenBank Nucleotide #

NM_020664.3

NCBI Official Full Name

peroxisomal 2,4-dienoyl-CoA reductase

NCBI Official Synonym Full Names

2,4-dienoyl CoA reductase 2, peroxisomal

NCBI Official Symbol

DECR2

NCBI Official Synonym Symbols

PDCR; SDR17C1

UniProt Protein Name

Peroxisomal 2,4-dienoyl-CoA reductase

UniProt Synonym Protein Names

2,4-dienoyl-CoA reductase 2

UniProt Gene Name

DECR2

UniProt Synonym Gene Names

PDCR; pDCR

UniProt Entry Name

DECR2_HUMAN

NCBI Protein Information

peroxisomal 2,4-dienoyl-CoA reductase; 2,4-dienoyl-CoA reductase 2; short chain dehydrogenase/reductase family 17C, member 1

UniProt Comments for DECR2

DECR2: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.3.1.34; Oxidoreductase

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: peroxisomal membrane

Molecular Function: 2,4-dienoyl-CoA reductase (NADPH) activity; receptor binding; trans-2-enoyl-CoA reductase (NADPH) activity

Biological Process: unsaturated fatty acid biosynthetic process

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DECR2 recombinant protein

Products by Pathway	Pathway Diagram
Peroxisome Pathway antibodies	Peroxisome Pathway Diagram
Peroxisome Pathway antibodies	Peroxisome Pathway Diagram

Diseases associated with DECR2 recombinant protein

Disease Name	Pubmed Publications
Weight Gain Antibodies	>1 publications with DECR2 and Weight Gain