Human RAB8 Recombinant Protein – Cat# MBS145541

RAB8 Human Recombinant Protein

Name: RAB8 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS145541
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145541

Description: RAB8 Human Recombinant produced in E Coli is a single polypeptide chain containing 227 amino acids (1-204) and having a molecular mass of 25.7kDa. RAB8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RAB8, Recombinant Protein

Full Product Name

Recombinant Human RAB8, Member RAS Oncogene Family

Product Gene Name

RAB8 recombinant protein

Product Synonym Names

RAB8 Human; RAB8, Member RAS Oncogene Family Human Recombinant; Ras-related protein Rab-8B; RAB8B

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMAK TYDY LFKLLLIGDS GVGKTCLLFR FSEDAFNTTF ISTIGIDFKI RTIELDGKKI KLQIWDTAGQ ERFRTITTAY YRGAMGIMLV YDITNEKSFD NIKNWIRNIE EHASSDVERM ILGNKCDMND KRQVSKERGE KLAIDYGIKF LETSAKSSAN VEEAFFTLAR DIMTKLNRKM NDSNSAGAGG PVKITENRSK KTSFFRC

Host

E Coli

Form/Format

The RAB8 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
Sterile Filtered clear solution.

Purity/Purification

Greater than 90% as determined by SDS-PAGE.

Molecular Weight

23,584 Da

OMIM

613532

3D Structure

ModBase 3D Structure for Q92930

Product Categories/Family for RAB8 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Member RAS Oncogene Family

Other Notes

Small volumes of RAB8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB8 purchase

MBS145541 is a recombinant protein targeting RAB8. Also known as Recombinant Human RAB8, Member RAS Oncogene Family. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB8. It may not necessarily be applicable to this product.

NCBI GI #

7706563

NCBI GeneID

51762

NCBI Accession #

NP_057614.1

UniProt Primary Accession #

Q92930

UniProt Secondary Accession #

Q5JPC4; Q9P293

UniProt Related Accession #

Q92930

GenBank Nucleotide #

NM_016530.2

NCBI Official Full Name

ras-related protein Rab-8B

NCBI Official Synonym Full Names

RAB8B, member RAS oncogene family

NCBI Official Symbol

RAB8B

UniProt Protein Name

Ras-related protein Rab-8B

Protein Family

Mitogen-activated protein kinase kinase kinase kinase

UniProt Gene Name

RAB8B

UniProt Entry Name

RAB8B_HUMAN

NCBI Protein Information

ras-related protein Rab-8B; RAB-8b protein

NCBI Summary for RAB8

RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010]

UniProt Comments for RAB8

RAB8B: May be involved in vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein; Motility/polarity/chemotaxis; G protein, monomeric; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: peroxisomal membrane; phagocytic vesicle membrane; trans-Golgi network transport vesicle; synaptic vesicle; mitochondrion; perinuclear region of cytoplasm; secretory granule membrane; plasma membrane; phagocytic vesicle; endosome

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; TPR domain binding; receptor binding

Biological Process: regulation of exocytosis; antigen processing and presentation; synaptic vesicle exocytosis; Golgi vesicle fusion to target membrane; cellular response to insulin stimulus; metabolic process; positive regulation of cell projection organization and biogenesis; protein secretion; cilium biogenesis; protein import into peroxisome membrane; Rab protein signal transduction; vesicle docking during exocytosis; positive regulation of adrenocorticotropic hormone secretion

Research Articles on RAB8

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RAB8 recombinant protein

Reference Product	PubMed Publications
RAB3IP recombinant protein	>1 publications with RAB8 and RAB3IP
OTOF recombinant protein	>1 publications with RAB8 and OTOF

Diseases associated with RAB8 recombinant protein

Disease Name	Pubmed Publications
Memory Disorders Antibodies	>1 publications with RAB8 and Memory Disorders
Hearing Loss Antibodies	>1 publications with RAB8 and Hearing Loss
Learning Disorders Antibodies	>1 publications with RAB8 and Learning Disorders
Atrophy Antibodies	>1 publications with RAB8 and Atrophy
Disease Models, Animal Antibodies	>1 publications with RAB8 and Disease Models, Animal

Organs/Tissues associated with RAB8 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>23 publications with RAB8 and Brain
Nerve Antibodies	>8 publications with RAB8 and Nerve
Kidney Antibodies	>4 publications with RAB8 and Kidney
Embryonic Tissue Antibodies	>3 publications with RAB8 and Embryonic Tissue
Spleen Antibodies	>2 publications with RAB8 and Spleen
Muscle Antibodies	>2 publications with RAB8 and Muscle
Eye Antibodies	>2 publications with RAB8 and Eye
Ear Antibodies	>2 publications with RAB8 and Ear
Testis Antibodies	>2 publications with RAB8 and Testis
Intestine Antibodies	>1 publications with RAB8 and Intestine