• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Osteoclast Associated (OSCAR) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145711

Description: OSCAR Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 291 amino acids (19-286 a.a.) and having a molecular mass of 31kDa.OSCAR is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Osteoclast Associated (OSCAR), Recombinant Protein
Full Product Name
Recombinant Human Osteoclast Associated, Immunoglobulin-Like Receptor
Product Gene Name
Product Synonym Names
OSCAR Human; Osteoclast Associated, Immunoglobulin-Like Receptor Human Recombinant; PIGR3; Osteoclast-associated immunoglobulin-like receptor; hOSCAR; Polymeric immunoglobulin receptor 3; OSCAR; PIgR-3; PIgR3; Poly-Ig receptor 3
Sequence
MGSSHHH HHH SSGLVPRGSH MGSDIT PSVA IIVPPASYHP KPWLGAQPAT VVTPGVNVTL RCRAPQPAWR FGLFKPGEIA PLLFRDVSSE LAEFFLEEVT PAQGGIYRCC YRRPDWGPGV WSQPSDVLEL LVTEELPRPS LVALPGPVVG PGANVSLRCA GRLRNMSFVL YREGVAAPLQ YRHSAQPWAD FTLLGARAPG TYSCYYHTPS APYVLSQRSE VLVISWEGEG PEARPASSAP GMQAPGPPPS DPGAQAPSLS SFRPRGLVLQ PLLPQTQDSW DPAPPPSDPG V
Host
E Coli
Form/Format
OSCAR protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.4M Urea and 10% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Molecular Weight
27,629 Da
OMIM
606862
3D Structure
ModBase 3D Structure for Q8IYS5

Other Notes

Small volumes of OSCAR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OSCAR purchase

MBS145711 is a recombinant protein targeting OSCAR. Also known as Recombinant Human Osteoclast Associated, Immunoglobulin-Like Receptor. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for OSCAR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
osteoclast-associated immunoglobulin-like receptor isoform 6
NCBI Official Synonym Full Names
osteoclast associated, immunoglobulin-like receptor
NCBI Official Symbol
OSCAR
NCBI Official Synonym Symbols
PIGR3; PIgR-3
UniProt Protein Name
Osteoclast-associated immunoglobulin-like receptor
UniProt Synonym Protein Names
Polymeric immunoglobulin receptor 3; PIgR-3; PIgR3; Poly-Ig receptor 3
UniProt Gene Name
OSCAR
UniProt Synonym Gene Names
Osteoclast-associated receptor; hOSCAR; PIgR-3; PIgR3; Poly-Ig receptor 3
UniProt Entry Name
OSCAR_HUMAN
NCBI Protein Information
osteoclast-associated immunoglobulin-like receptor; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; poly-Ig receptor 3; polymeric immunoglobulin receptor 3

NCBI Summary for OSCAR

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
Show more

UniProt Comments for OSCAR

OSCAR: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. Belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: plasma membrane; integral to membrane
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000