• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

RAB10 Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS145756

Description: RAB10 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 220 amino acids (1-200) and having a molecular mass of 24.7 kDa. RAB10 is fused to a 20 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RAB10, Recombinant Protein
Full Product Name
Recombinant Human RAB10, Member RAS Oncogene Family
Product Gene Name
RAB10 recombinant protein
Product Synonym Names
RAB10 Human; RAB10, Member RAS Oncogene Family Human Recombinant; Ras-related GTP-binding protein RAB10; Ras-related protein Rab-10; RAB10; Rab10; member RAS oncogene family
Sequence
MGSSHHH HHH SSGLVPRGSH MAKKTYDLLF KLLLIGDSGV GKTCVLFRFS DDAFNTTFIS TIGIDFKIKT VELQGKKIKL QIWDTAGQER FHTITTSYYR GAMGIMLVYD ITNGKSFENI SKWLRNIDEH ANEDVERMLL GNKCDMDDKR VVPKGKGEQI AREHGIRFFE TSAKANINIE KAFLTLAEDI LRKTPVKEPN SENVDISSGG GVTGWKSKCC .
Host
E Coli
Form/Format
The RAB10 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol 0.4M Urea.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Molecular Weight
22,541 Da
OMIM
612672
3D Structure
ModBase 3D Structure for P61026

Product Categories/Family for RAB10 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Member RAS Oncogene Family

Other Notes

Small volumes of RAB10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB10 purchase

MBS145756 is a recombinant protein targeting RAB10. Also known as Recombinant Human RAB10, Member RAS Oncogene Family. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB10. It may not necessarily be applicable to this product.

NCBI GI #
256222019
NCBI GeneID
10890
NCBI Accession #
NP_057215.3
UniProt Primary Accession #
P61026
UniProt Secondary Accession #
O88386; Q6IA52; Q9D7X6; Q9H0T3; D6W538
UniProt Related Accession #
P61026
GenBank Nucleotide #
NM_016131.4
NCBI Official Full Name
ras-related protein Rab-10
NCBI Official Synonym Full Names
RAB10, member RAS oncogene family
NCBI Official Symbol
RAB10
UniProt Protein Name
Ras-related protein Rab-10
Protein Family
Ras-related protein
UniProt Gene Name
RAB10
UniProt Entry Name
RAB10_HUMAN
NCBI Protein Information
ras-related protein Rab-10; GTP-binding protein RAB10; ras-related GTP-binding protein

NCBI Summary for RAB10

RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009]

UniProt Comments for RAB10

RAB10: a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor.

Protein type: G protein, monomeric, Rab; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: Golgi apparatus; recycling endosome; endoplasmic reticulum membrane; phagocytic vesicle membrane; cytoplasmic vesicle membrane; focal adhesion; recycling endosome membrane; exocyst; plasma membrane; endosome membrane; trans-Golgi network; endosome

Molecular Function: GTPase activity; GDP binding; GTP binding; myosin V binding

Biological Process: metabolic process; establishment of neuroblast polarity; protein secretion; endosome transport; regulation of exocytosis; vesicle-mediated transport; intracellular protein transport; polarized epithelial cell differentiation; antigen processing and presentation; Golgi to plasma membrane transport; cellular response to insulin stimulus; axonogenesis; Golgi to plasma membrane protein transport; Rab protein signal transduction; vesicle docking during exocytosis
Show more

Research Articles on RAB10

1. Rab10 silencing increased the plasma membrane residence of HAS3, resulting in a significant increase of hyaluronan secretion and an enlarged cell surface HA coat, whereas Rab10 overexpression suppressed hyaluronan synthesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RAB10 recombinant protein

 Reference Product  PubMed Publications
 RAB8A recombinant protein  >16 publications with RAB10 and RAB8A
 SLC2A4 recombinant protein  >7 publications with RAB10 and SLC2A4
 TBC1D4 recombinant protein  >7 publications with RAB10 and TBC1D4
 MYO5A recombinant protein  >3 publications with RAB10 and MYO5A
 TBC1D1 recombinant protein  >2 publications with RAB10 and TBC1D1

Pathways associated with RAB10 recombinant protein

 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Translocation Of GLUT4 To The Plasma Membrane Pathway antibodies  Translocation Of GLUT4 To The Plasma Membrane Pathway Diagram

Diseases associated with RAB10 recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with RAB10 and Inflammation
 Carcinoma, Hepatocellular Antibodies  >1 publications with RAB10 and Carcinoma, Hepatocellular
 Weight Loss Antibodies  >1 publications with RAB10 and Weight Loss
 Liver Diseases Antibodies  >1 publications with RAB10 and Liver Diseases
 Ovarian Diseases Antibodies  >1 publications with RAB10 and Ovarian Diseases
 Edema Antibodies  >1 publications with RAB10 and Edema
 Fibrosis Antibodies  >1 publications with RAB10 and Fibrosis
 Liver Neoplasms Antibodies  >1 publications with RAB10 and Liver Neoplasms
 Disease Models, Animal Antibodies  >1 publications with RAB10 and Disease Models, Animal

Organs/Tissues associated with RAB10 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >11 publications with RAB10 and Muscle
 Brain Antibodies  >9 publications with RAB10 and Brain
 Kidney Antibodies  >5 publications with RAB10 and Kidney
 Liver Antibodies  >4 publications with RAB10 and Liver
 Intestine Antibodies  >3 publications with RAB10 and Intestine
 Eye Antibodies  >2 publications with RAB10 and Eye
 Lung Antibodies  >2 publications with RAB10 and Lung
 Placenta Antibodies  >2 publications with RAB10 and Placenta
 Bone Marrow Antibodies  >1 publications with RAB10 and Bone Marrow
 Ovary Antibodies  >1 publications with RAB10 and Ovary
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000