Human RNASE7 Recombinant Protein – Cat# MBS146191

Ribonuclease 7 (RNASE7) Human Recombinant Protein

Name: RNASE7 Recombinant Protein; Ribonuclease 7; Human; MyBioSource
Brand: MyBioSource
SKU: MBS146191
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146191

RNASE7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 151 amino acids (29-156 a.a) and having a molecular mass of 16.9kDa.RNASE7 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ribonuclease 7 (RNASE7), Recombinant Protein

Full Product Name

Recombinant Human Ribonuclease 7

Product Gene Name

RNASE7 recombinant protein

Product Synonym Names

Ribonuclease, RNase A Family, 7, Skin-Derived Antimicrobial Protein 2, RNase 7, SAP-2, EC 3.1.27.5, EC 3.1.27., EC 3.1.27, Ribonuclease 7

Sequence

MGSSHHH HHHSSGLVPR GSH MGSKPK GMTS SQWFKIQHMQ PSPQACNSAM KNINKHTKRC KDLNTFLHEP FSSVAATCQT PKIACKNGDK NCHQSHGPVS LTMCKLTSGK YPNCRYKEKR QNKSYVVACK PPQKKDSQQF HLVPVHLDRV L

Host

Escherichia Coli.

Form/Format

RNASE7 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol 1mM DTT.solution.

Purity/Purification

Greater than 90% as determined by SDS-PAGE.

Preparation and Storage

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Avoid multiple freeze-thaw cycles

OMIM

612484

Physical Appearance

Sterile Filtered colorless

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSKPKGMTS SQWFKIQHMQ PSPQACNSAM KNINKHTKRC KDLNTFLHEP FSSVAATCQT PKIACKNGDK NCHQSHGPVS LTMCKLTSGK YPNCRYKEKR QNKSYVVACK PPQKKDSQQF HLVPVHLDRV L.

Product Categories/Family for RNASE7 recombinant protein

Enzymes

Other Notes

Small volumes of RNASE7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RNASE7 purchase

MBS146191 is a recombinant protein targeting RNASE7. Also known as Recombinant Human Ribonuclease 7. Host: Escherichia Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RNASE7. It may not necessarily be applicable to this product.

NCBI GI #

153252081

NCBI GeneID

84659

NCBI Accession #

NP_115961.2

UniProt Secondary Accession #

P80927; P83685; Q546N3

UniProt Related Accession #

Q9H1E1

GenBank Nucleotide #

NM_032572.3

NCBI Official Full Name

ribonuclease 7

NCBI Official Synonym Full Names

ribonuclease, RNase A family, 7

NCBI Official Symbol

RNASE7

UniProt Protein Name

Ribonuclease 7

UniProt Synonym Protein Names

Skin-derived antimicrobial protein 2; SAP-2

Protein Family

Ribonuclease

UniProt Gene Name

RNASE7

UniProt Synonym Gene Names

RNase 7; SAP-2

UniProt Entry Name

RNAS7_HUMAN

NCBI Protein Information

ribonuclease 7; RNase 7; SAP-2; skin-derived antimicrobial protein 2

NCBI Summary for RNASE7

The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein has broad-spectrum antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]

UniProt Comments for RNASE7

RNASE7: Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Belongs to the pancreatic ribonuclease family.

Protein type: Ribonuclease; Secreted; EC 3.1.27.-; RNA-binding; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: extracellular region

Molecular Function: peptidoglycan binding; nucleic acid binding; lipopolysaccharide binding; endonuclease activity; ribonuclease activity

Biological Process: defense response to Gram-positive bacterium; response to bacterium; antibacterial humoral response; innate immune response; membrane disruption in another organism; defense response to Gram-negative bacterium

Research Articles on RNASE7

1. RNH1 bound to RNase 7 and suppressed its antimicrobial activity by blocking its ability to bind the cell wall of uropathogenic bacteria.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RNASE7 recombinant protein

Reference Product	PubMed Publications
S100A7 recombinant protein	>23 publications with RNASE7 and S100A7
DEFB4A recombinant protein	>18 publications with RNASE7 and DEFB4A
RNH1 recombinant protein	>1 publications with RNASE7 and RNH1

Diseases associated with RNASE7 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>10 publications with RNASE7 and Inflammation
Kidney Diseases Antibodies	>3 publications with RNASE7 and Kidney Diseases
Immune System Diseases Antibodies	>3 publications with RNASE7 and Immune System Diseases
Death Antibodies	>2 publications with RNASE7 and Death
Carcinoma Antibodies	>1 publications with RNASE7 and Carcinoma
Precancerous Conditions Antibodies	>1 publications with RNASE7 and Precancerous Conditions
Skin Neoplasms Antibodies	>1 publications with RNASE7 and Skin Neoplasms
Necrosis Antibodies	>1 publications with RNASE7 and Necrosis

Organs/Tissues associated with RNASE7 recombinant protein

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>44 publications with RNASE7 and Skin
Liver Antibodies	>3 publications with RNASE7 and Liver
Heart Antibodies	>1 publications with RNASE7 and Heart