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Cerebral Dopamine Neurotrophic Factor (rCDNF) Rat Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146217

Description: CDNF Rat Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 163 amino acids and having a molecular mass of 18.8kDa.The CDNF is purified by proprietary chromatographic techniques.Introduction: CDNF is a… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cerebral Dopamine Neurotrophic Factor (rCDNF), Active Protein
Full Product Name
Recombinant Rat Cerebral Dopamine Neurotrophic Factor
Product Gene Name
Product Synonym Names
CDNF Rat; Cerebral Dopamine Neurotrophic Factor Rat Recombinant; Cerebral dopamine neurotrophic factor; ARMET-like protein 1; Arginine-rich protein mutated in early stage tumors-like 1; Conserved dopamine neurotrophic factor; Cdnf; Armetl1
Sequence
QGLEAGVRSR ADCEVCKEFL NRFYNSLLTR GIDFSVDTIE EELISFCADT KGKENRLCYY LGATKDSATK ILGEVTRPMS VHMPTVKICE KLKKMDSQIC ELKYEKKLDL ESVDLWKMRV AELKQILHSW GEECRACAEK HDYVNLIKEL APKYVETRPQ TEL
Host
E Coli
Form/Format
CDNF protein was lyophilized from a 0.2 um filtered concentrated solution in 1xPBS, pH 7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity/Purification
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Preparation and Storage
Lyophilized CDNF although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CDNF should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Molecular Weight
21,361 Da
3D Structure
ModBase 3D Structure for P0C5I0
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Solubility
It is recommended to reconstitute the lyophilized CDNF in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
CDNF Rat is able to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons when immobilized at 5-25 ug/mL on a nitrocellulose-coated microplate.

Other Notes

Small volumes of rCDNF active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for rCDNF purchase

MBS146217 is an active protein targeting rCDNF. Also known as Recombinant Rat Cerebral Dopamine Neurotrophic Factor. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for rCDNF. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cerebral dopamine neurotrophic factor
NCBI Official Synonym Full Names
cerebral dopamine neurotrophic factor
NCBI Official Symbol
Cdnf
NCBI Official Synonym Symbols
Armetl1
UniProt Protein Name
Cerebral dopamine neurotrophic factor
UniProt Synonym Protein Names
ARMET-like protein 1; Arginine-rich protein mutated in early stage tumors-like 1; Conserved dopamine neurotrophic factor
UniProt Gene Name
Cdnf
UniProt Synonym Gene Names
Armetl1
UniProt Entry Name
CDNF_RAT
NCBI Protein Information
cerebral dopamine neurotrophic factor; ARMET-like protein 1; arginine-rich protein mutated in early stage tumors-like 1; arginine-rich, mutated in early stage tumors-like 1; conserved dopamine neurotrophic factor

UniProt Comments for rCDNF

Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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