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Axin Interactor Dorsalization Associated (AIDA) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146363

Description: AIDA Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 329 amino acids (1-306 a.a) and having a molecular mass of 37.4kDa. AIDA is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

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Product Overview

Online Datasheet in PDF
Product Name
Axin Interactor Dorsalization Associated (AIDA), Recombinant Protein
Full Product Name
Recombinant Human Axin Interactor Dorsalization Associated
Product Gene Name
Product Synonym Names
AIDA Human; Axin Interactor Dorsalization Associated Human Recombinant; C1orf80; RP11-378J18.7; Axin interactor; dorsalization-associated protein; Axin interaction partner and dorsalization antagonist; AIDA
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMSE VTRS LLQRWGASFR RGADFDSWGQ LVEAIDEYQI LARHLQKEAQ AQHNNSEFTE EQKKTIGKIA TCLELRSAAL QSTQSQEEFK LEDLKKLEPI LKNILTYNKE FPFDVQPVPL RRILAPGEEE NLEFEEDEEE GGAGAGSPDS FPARVPGTLL PRLPSEPGMT LLTIRIEKIG LKDAGQCIDP YITVSVKDLN GIDLTPVQDT PVASRKEDTY VHFNVDIELQ KHVEKLTKGA AIFFEFKHYK PKKRFTSTKC FAFMEMDEIK PGPIVIELYK KPTDFKRKKL QLLTKKPLYL HLHQTLHKE
Host
E Coli
Form/Format
AIDA protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.2M NaCl and 1mM DTT.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Molecular Weight
25,914 Da
OMIM
612375
3D Structure
ModBase 3D Structure for Q96BJ3

Other Notes

Small volumes of AIDA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AIDA purchase

MBS146363 is a recombinant protein targeting AIDA. Also known as Recombinant Human Axin Interactor Dorsalization Associated. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for AIDA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
axin interactor, dorsalization-associated protein
NCBI Official Synonym Full Names
axin interactor, dorsalization associated
NCBI Official Symbol
AIDA
NCBI Official Synonym Symbols
C1orf80
UniProt Protein Name
Axin interactor, dorsalization-associated protein
UniProt Synonym Protein Names
Axin interaction partner and dorsalization antagonist
UniProt Gene Name
AIDA
UniProt Synonym Gene Names
C1orf80
UniProt Entry Name
AIDA_HUMAN
NCBI Protein Information
axin interactor, dorsalization-associated protein; axin interaction partner and dorsalization antagonist

UniProt Comments for AIDA

AIDA: Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling. Belongs to the AIDA family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: cytoplasm

Molecular Function: protein domain specific binding

Biological Process: negative regulation of JNK cascade; negative regulation of JNK activity; dorsal/ventral pattern formation; regulation of protein homodimerization activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with AIDA recombinant protein

 Reference Product  PubMed Publications
 MKS1 recombinant protein  >1 publications with AIDA and MKS1
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