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Meprin A Subunit Alpha (MEP1A) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS146927

Description: MEP1A produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 589 amino acids (22-601 a.a.) and having a molecular mass of 67.4kDa (Molecular size on SDS-PAGE will appear at approximately 70-100kDa). MEP1A is… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Meprin A Subunit Alpha (MEP1A), Recombinant Protein
Full Product Name
Recombinant Human Meprin A Subunit Alpha
Product Gene Name
MEP1A recombinant protein
Product Synonym Names
MEP1A Human; Meprin A Subunit Alpha; PABA Peptide Hydrolase; N-Benzoyl-L-Tyrosyl-P-Amino-Benzoic Acid Hydrolase Subunit Alpha; Meprin A; Alpha (PABA Peptide Hydrolase); Endopeptidase-2; EC 3.4.24.18; PPH Alpha; BA268F1.1 (Meprin A Alpha (PABA Peptide Hydrolase)); EC 3.4.24; PPHA; MEP1A; Meprin A Subunit Alpha Human Recombinant
Sequence
ADP VPIKYLP EENVHDADFG EQKDISEINL AAGLDLFQGD ILLQKSRNGL RDPNTRWTFP IPYILADNLG LNAKGAILYA FEMFRLKSCV DFKPYEGESS YIIFQQFDGC WSEVGDQHVG QNISIGQGCA YKAIIEHEIL HALGFYHEQS RTDRDDYVNI WWDQILSGYQ HNFDTYDDSL ITDLNTPYDY ESLMHYQPFS FNKNASVPTI TAKIPEFNSI IGQRLDFSAI DLERLNRMYN CTTTHTLLDH CTFEKANICG MIQGTRDDTD WAHQDSAQAG EVDHTLLGQC TGAGYFMQFS TSSGSAEEAA LLESRILYPK RKQQCLQFFY KMTGSPSDRL VVWVRRDDST GNVRKLVKVQ TFQGDDDHNW KIAHVVLKEE QKFRYLFQGT KGDPQNSTGG IYLDDITLTE TPCPTGVWTV RNFSQVLENT SKGDKLQSPR FYNSEGYGFG VTLYPNSRES SGYLRLAFHV CSGENDAILE WPVENRQVII TILDQEPDVR NRMSSSMVFT TSKSHTSPAI NDTVIWDRPS RVGTYHTDCN CFRSIDLGWS GFISHQMLKR RSFLKNDDLI IFVDFEDITH LSQHHHH HH.
Host
Sf9, Baculovirus cells
Form/Format
Sterile filtered colorless solution.
MEP1A protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Molecular Weight
84,419 Da
OMIM
M82962 mRNA
3D Structure
ModBase 3D Structure for Q16819

Product Categories/Family for MEP1A recombinant protein

Recombinant & Natural Proteins

Other Notes

Small volumes of MEP1A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MEP1A purchase

MBS146927 is a recombinant protein targeting MEP1A. Also known as Recombinant Human Meprin A Subunit Alpha. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for MEP1A. It may not necessarily be applicable to this product.

NCBI GI #
153070262
NCBI GeneID
4224
NCBI Accession #
NP_005579.2
UniProt Primary Accession #
Q16819
UniProt Secondary Accession #
Q8TDC9; Q9H1R1; A2RRM4; B0AZP9; B2RCS2
UniProt Related Accession #
Q16819
GenBank Nucleotide #
NM_005588.2
NCBI Official Full Name
meprin A subunit alpha
NCBI Official Synonym Full Names
meprin A subunit alpha
NCBI Official Symbol
MEP1A
NCBI Official Synonym Symbols
PPHA
UniProt Protein Name
Meprin A subunit alpha
UniProt Synonym Protein Names
Endopeptidase-2; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha; PABA peptide hydrolase; PPH alpha
Protein Family
Meprin
UniProt Gene Name
MEP1A
NCBI Protein Information
meprin A subunit alpha

UniProt Comments for MEP1A

MEP1A: Belongs to the peptidase M12A family.

Protein type: EC 3.4.24.18; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 6p12.3

Cellular Component: extracellular space; integral to plasma membrane

Molecular Function: protein binding

Biological Process: digestion

Research Articles on MEP1A

1. Variants rs17468190 (G/T) in the MEP1A gene are associated with glucose and insulin metabolism in overweight/obese central European women with polycystic ovary syndrome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MEP1A recombinant protein

 Reference Product  PubMed Publications
 MEP1B recombinant protein  >5 publications with MEP1A and MEP1B
 CDX2 recombinant protein  >2 publications with MEP1A and CDX2
 PTH recombinant protein  >1 publications with MEP1A and PTH

Pathways associated with MEP1A recombinant protein

 Products by Pathway  Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram

Diseases associated with MEP1A recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >6 publications with MEP1A and Inflammation
 Obesity Antibodies  >1 publications with MEP1A and Obesity
 Liver Diseases Antibodies  >1 publications with MEP1A and Liver Diseases
 Fibrosis Antibodies  >1 publications with MEP1A and Fibrosis
 Kidney Diseases Antibodies  >1 publications with MEP1A and Kidney Diseases
 Necrosis Antibodies  >1 publications with MEP1A and Necrosis

Organs/Tissues associated with MEP1A recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >5 publications with MEP1A and Intestine
 Liver Antibodies  >1 publications with MEP1A and Liver
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