Human CEACAM3 Recombinant Protein – Cat# MBS147232

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3) Human Recombinant Protein

Name: CEACAM3 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS147232
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS147232

Description: CEACAM3 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 130 amino acids (35-155a.a.) and having a molecular mass of 14.2kDa (Molecular size on SDS-PAGE will appear at approximately… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3), Recombinant Protein

Full Product Name

Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3

Product Gene Name

CEACAM3 recombinant protein

Product Synonym Names

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3; Carcinoembryonic Antigen CGM1; CD66d Antigen; CD66D; CGM1; Carcinoembryonic Antigen Gene Family Member 1; Nonspecific Cross-Reacting Antigen; W264; W282; CEA; CEACAM3; CEACAM3 Human, Sf9; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 Human Recombinant, Sf9

Sequence

ADP KLTIESM PLSVAEGKEV LLLVHNLPQH LFGYSWYKGE RVDGNSLIVG YVIGTQQATP GAAYSGRETI YTNASLLIQN VTQNDIGFYT LQVIKSDLVN EEATGQFHVY QENAPGLPVG AVAGHHHHHH

Host

Sf9, Baculovirus cells

Form/Format

Sterile filtered colorless solution
Protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles

Molecular Weight

22,754 Da

OMIM

D90277 mRNA

3D Structure

ModBase 3D Structure for P40198

Product Categories/Family for CEACAM3 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; CEA; CEACAM3 Human; Sf9

Other Notes

Small volumes of CEACAM3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CEACAM3 purchase

MBS147232 is a recombinant protein targeting CEACAM3. Also known as Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3. Host: Sf9, Baculovirus cells.

Additional Details

NCBI/Uniprot data below describe general gene information for CEACAM3. It may not necessarily be applicable to this product.

NCBI GI #

218511974

NCBI GeneID

1084

NCBI Accession #

P40198.2

UniProt Primary Accession #

P40198

UniProt Secondary Accession #

Q3KPH9; G5E978

UniProt Related Accession #

P40198

NCBI Official Full Name

Carcinoembryonic antigen-related cell adhesion molecule 3

NCBI Official Synonym Full Names

carcinoembryonic antigen related cell adhesion molecule 3

NCBI Official Symbol

CEACAM3

NCBI Official Synonym Symbols

CEA; CGM1; W264; W282; CD66D

UniProt Protein Name

Carcinoembryonic antigen-related cell adhesion molecule 3

UniProt Synonym Protein Names

Carcinoembryonic antigen CGM1; CD_antigen: CD66d

Protein Family

Carcinoembryonic antigen-related cell adhesion molecule

UniProt Gene Name

CEACAM3

UniProt Synonym Gene Names

CD66D; CGM1

NCBI Protein Information

carcinoembryonic antigen-related cell adhesion molecule 3

NCBI Summary for CEACAM3

This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]

UniProt Comments for CEACAM3

Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.

Research Articles on CEACAM3

1. Here, the authors identify members of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as receptors of Helicobacter pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CEACAM1, CEACAM3, CEACAM5 and CEACAM6.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CEACAM3 recombinant protein

Reference Product	PubMed Publications
CEACAM1 recombinant protein	>31 publications with CEACAM3 and CEACAM1
SRC recombinant protein	>12 publications with CEACAM3 and SRC
VAV1 recombinant protein	>1 publications with CEACAM3 and VAV1

Diseases associated with CEACAM3 recombinant protein

Disease Name	Pubmed Publications
Necrosis Antibodies	>4 publications with CEACAM3 and Necrosis
Inflammation Antibodies	>3 publications with CEACAM3 and Inflammation
Lung Diseases Antibodies	>3 publications with CEACAM3 and Lung Diseases
Adenocarcinoma Antibodies	>2 publications with CEACAM3 and Adenocarcinoma
Neoplasms, Experimental Antibodies	>2 publications with CEACAM3 and Neoplasms, Experimental
Pneumonia Antibodies	>1 publications with CEACAM3 and Pneumonia

Organs/Tissues associated with CEACAM3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>26 publications with CEACAM3 and Blood
Spleen Antibodies	>2 publications with CEACAM3 and Spleen
Placenta Antibodies	>1 publications with CEACAM3 and Placenta