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U2 Small Nuclear Ribonucleoprotein Auxiliary Factor 35 Kda Subunit-Related Protein 2 (ZRSR2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1472931

This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3 splice site in pre-mRNA splicing, and may play a role in network interactions… More details

$1265 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 (ZRSR2), Recombinant Protein
Full Product Name
Recombinant Human U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 (ZRSR2)
Product Gene Name
ZRSR2 recombinant protein
Product Synonym Gene Name
ZRSR2
Sequence
MAAPEKMTFP EKPSHKKYRA ALKKEKRKKR RQELARLRDS GLSQKEEEED TFIEEQQLEE EKLLERERQR LHEEWLLREQ KAQEEFRIKK EKEEAAKKRQ EEQERKLKEQ WEEQQRKERE EEEQKRQEKK EKEEALQKML DQAENELENG TTWQNPEPPV DFRVMEKDRA NCPFYSKTGA CRFGDRCSRK HNFPTSSPTL LIKSMFTTFG MEQCRRDDYD PDASLEYSEE ETYQQFLDFY EDVLPEFKNV GKVIQFKVSC NLEPHLRGNV YVQYQSEEEC QAALSLFNGR WYAGRQLQCE FCPVTRWKMA ICGLFEIQQC PRGKHCNFLH VFRNPNNEFW EANRDIYLSP DRTGSSFGKN SERRERMGHH DDYYSRLRGR RNPSPDHSYK RNGESERKSS RHRGKKSHKR TSKSRERHNS RSRGRNRDRS RDRSRGRGSR SRSRSRSRRS RRSRSQSSSR SRSRGRRRSG NRDRTVQSPK SK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
58,045 Da
Sequence Positions
1-482, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
300028
3D Structure
ModBase 3D Structure for Q15696
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ZRSR2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZRSR2 purchase

MBS1472931 is a recombinant protein targeting ZRSR2. Also known as Recombinant Human U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 (ZRSR2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for ZRSR2. It may not necessarily be applicable to this product.

NCBI GI #
4827046
NCBI GeneID
8233
NCBI Accession #
NP_005080.1
UniProt Primary Accession #
Q15696
UniProt Secondary Accession #
Q14D69
UniProt Related Accession #
Q15696
GenBank Nucleotide #
NM_005089.3
NCBI Official Full Name
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2
NCBI Official Synonym Full Names
zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
NCBI Official Symbol
ZRSR2
NCBI Official Synonym Symbols
URP; ZC3H22; U2AF1L2; U2AF1RS2; U2AF1-RS2
UniProt Protein Name
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2
UniProt Synonym Protein Names
CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2; Renal carcinoma antigen NY-REN-20; U2(RNU2) small nuclear RNA auxiliary factor 1-like 2; U2AF35-related protein; URP
Protein Family
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein
UniProt Gene Name
ZRSR2
UniProt Synonym Gene Names
U2AF1-RS2; U2AF1L2; U2AF1RS2; URP; URP
NCBI Protein Information
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

NCBI Summary for ZRSR2

This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008]
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UniProt Comments for ZRSR2

Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3'-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.
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Research Articles on ZRSR2

1. We conclude that the common clinical features of patients with an isolated mutation of ZRSR2 are a macrocytic anemia without leukopenia, thrombocytopenia or an increase in marrow blast percentage

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ZRSR2 recombinant protein

 Reference Product  PubMed Publications
 U2AF1 recombinant protein  >6 publications with ZRSR2 and U2AF1
 SRSF2 recombinant protein  >3 publications with ZRSR2 and SRSF2

Diseases associated with ZRSR2 recombinant protein

 Disease Name  Pubmed Publications
 Bone Marrow Diseases Antibodies  >3 publications with ZRSR2 and Bone Marrow Diseases
 Neoplasms Antibodies  >2 publications with ZRSR2 and Neoplasms

Organs/Tissues associated with ZRSR2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with ZRSR2 and Lung
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