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Ap-4 Complex Subunit Mu-1 (AP4M1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1475590

This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the… More details

$1220 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AP-4 complex subunit mu-1 (Ap4m1), Recombinant Protein
Full Product Name
Recombinant Mouse AP-4 complex subunit mu-1 (Ap4m1)
Product Gene Name
Ap4m1 recombinant protein
Product Synonym Gene Name
Ap4m1
Sequence
MISQFFILSS KGDPLIYKDF RGDSGGRDVA ELFYRKLTGL PGGESPVVMY HGDRHFIHIR HSGLYLVATT LENVSPFSLL ELLSRLATLL GDYCGSLNEG TISRNVALVY ELLDEVLDYG YVQTTSTEML RNFIQTEAVV SKPFSLFDLS SVGLFGAETQ QNKVAPSSAA SRPVLSSRSD QSQKNEVFLD VVERLSVLIA SNGSLLKVDV QGEIRLKSFL PSGSEICIGL TEEFCVGKSE LRGYGPGIRV DEVSFHSSVN LDEFESHRIL RLQPPQGELT VMRYQLSDDL PSPLPFRLFP SVQWDQGSGR LQVYLKLRCD LPPKSQALNI HLHLPLPRGV ISLSQELSSP DQKAELGEGA LHWDLPRVQG GSQLSGLFQM DVPGLQGLPN HGPSPLGLGP ASLSFELPRH TCSGLQVRFL RLSFSACGNA NPHKWVRHLS HSNAYVIRI
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
49,509 Da
Sequence Positions
1-449, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9JKC7
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ap4m1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ap4m1 purchase

MBS1475590 is a recombinant protein targeting Ap4m1. Also known as Recombinant Mouse AP-4 complex subunit mu-1 (Ap4m1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Ap4m1. It may not necessarily be applicable to this product.

NCBI GI #
163644298
NCBI GeneID
11781
NCBI Accession #
NP_067367.3
UniProt Primary Accession #
Q9JKC7
UniProt Related Accession #
Q9JKC7
GenBank Nucleotide #
NM_021392.4
NCBI Official Full Name
AP-4 complex subunit mu-1
NCBI Official Synonym Full Names
adaptor-related protein complex AP-4, mu 1
NCBI Official Symbol
Ap4m1
NCBI Official Synonym Symbols
Ap4m4; 4930443L05Rik
UniProt Protein Name
AP-4 complex subunit mu-1
UniProt Synonym Protein Names
AP-4 adaptor complex mu subunit; Adaptor-related protein complex 4 subunit mu-1; Mu subunit of AP-4; Mu-adaptin-related protein 2; mu-ARP2; Mu4-adaptin; mu4
Protein Family
AP-4 complex
UniProt Gene Name
Ap4m1
UniProt Synonym Gene Names
mu-ARP2; mu4
NCBI Protein Information
AP-4 complex subunit mu-1

UniProt Comments for Ap4m1

Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (). It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons (PubMed:18341993). Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Ap4m1 recombinant protein

 Products by Pathway  Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram

Diseases associated with Ap4m1 recombinant protein

 Disease Name  Pubmed Publications
 Atrophy Antibodies  >1 publications with Ap4m1 and Atrophy

Organs/Tissues associated with Ap4m1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with Ap4m1 and Brain
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