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FAST Kinase Domain-Containing Protein 3 (FASTKD3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1486765

MBS1486765 is a recombinant protein targeting FASTKD3. Also known as Recombinant Human FAST kinase domain-containing protein 3 (FASTKD3). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1495 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FAST kinase domain-containing protein 3 (FASTKD3), Recombinant Protein
Full Product Name
Recombinant Human FAST kinase domain-containing protein 3 (FASTKD3)
Product Gene Name
FASTKD3 recombinant protein
Product Synonym Gene Name
FASTKD3
Sequence
MALITLRKNL YRLSDFQMHR ALAALKNKPL NHVHKVVKER LCPWLCSRQP EPFGVKFHHA HCKKFHSKNG NDLHPLGGPV FSQVSDCDRL EQNVKNEESQ MFYRRLSNLT SSEEVLSFIS TMETLPDTMA AGALQRICEV EKKDGDQGLP KEILENSIFQ ALCFQFEKEP SQLSNTSLVT ALQALILLHV DPQSSLLLNL VAECQNRLRK GGMEVRNLCI LGESLITLHS SGCVTLELII NQLQGEKLET FTPEDIVALY RILQACTEKV DEHQTFLNKI NNFSLSIVSN LSPKLISQML TALVVLDQSQ AFPLIIKLGK YVVRHVPHFT NEELRRVLEA FIYFGHHDTF FTKALEHRVA AVCLTLDPEV VCRVMEYCSR ELILSKPILN AVAETFVCQT EKFSPRQISA LMEPFGKLNY LPPNASALFR KLENVLFTHF NYFPPKSLLK LLHSCSLNEC HPVNFLAKIF KPLFLQRLQG KESHLDTLSR AQLTQLFLAS VLECPFYKGP KLLPKYQVKS FLTPCCSLET PVDSQLYRYV KIGLTNLLGA RLYFAPKVLT PYCYTIDVEI KLDEEGFVLP STANEDIHKR IALCIDGPKR FCSNSKHLLG KEAIKQRHLQ LLGYQVVQIP YHEIGMLKSR RELVEYLQRK LFSQNTVHWL QE
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
75,689 Da
Sequence Positions
1-662, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
617530
3D Structure
ModBase 3D Structure for Q14CZ7
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FASTKD3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FASTKD3. It may not necessarily be applicable to this product.

NCBI GI #
40068497
NCBI GeneID
79072
NCBI Accession #
NP_076996.2
UniProt Primary Accession #
Q14CZ7
UniProt Secondary Accession #
Q9BVD3
UniProt Related Accession #
Q14CZ7
GenBank Nucleotide #
NM_024091.3
NCBI Official Full Name
FAST kinase domain-containing protein 3, mitochondrial
NCBI Official Synonym Full Names
FAST kinase domains 3
NCBI Official Symbol
FASTKD3
UniProt Protein Name
FAST kinase domain-containing protein 3, mitochondrial
Protein Family
FAST kinase domain-containing protein
UniProt Gene Name
FASTKD3
NCBI Protein Information
FAST kinase domain-containing protein 3, mitochondrial

NCBI Summary for FASTKD3

This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
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UniProt Comments for FASTKD3

Required for normal mitochondrial respiration (PubMed:20869947). Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity (PubMed:27789713).
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Research Articles on FASTKD3

1. Despite the fact that proteins of the FASTK family FASTKD1-5 share the same domains, they exhibit various-sometimes opposing-functions in almost all steps of mitochondrial RNA metabolism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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