Rabbit Anti-SOSS Polyclonal Antibody – Cat# MBS1492553

Western blot
All lanes: SOSS complex subunit B2 antibody at 2ug/ml
Lane 1:Hela whole cell lysate
Lane 2:jurkat whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 23,14,15 kDa
Observed band size: 22 kDa

Complex Subunit B2 (SOSS) Antibody – Rabbit Polyclonal

Name: SOSS Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1492553
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1492553

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to… More details

$230 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SOSS complex subunit B2, Polyclonal Antibody

Full Product Name

Rabbit anti-human SOSS complex subunit B2 polyclonal Antibody

Product Gene Name

anti-SOSS antibody

Product Synonym Names

Nucleic acid-binding protein 1; Oligonucleotide/oligosaccharide-binding fold-containing protein 2A; Sensor of single-strand DNA complex subunit B2; Sensor of ssDNA subunit B2; SOSS-B2; Single-stranded DNA-binding protein 2; hSSB2; NABP1; OBFC2A; SSB2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

Caprylic Acid Ammonium Sulfate Precipitation Purified

Preparation and Storage

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Matching Pairs

Unconjugated Antibody: SOSS (MBS1492553)
HRP Conjugated Antibody: SOSS (MBS968961)

Matching Pairs

Unconjugated Antibody: SOSS (MBS1492553)
FITC Conjugated Antibody: SOSS (MBS1492314)

Molecular Weight

14,677 Da

OMIM

612103

3D Structure

ModBase 3D Structure for Q96AH0

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Conjugate

Non-conjugated

Immunogen

Recombinant human SOSS complex subunit B2 protein(1-204aa)

Santa Cruz Alternative

Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-168821

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-SOSS antibody

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-SOSS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SOSS purchase

MBS1492553 is an antibody targeting SOSS. Also known as Rabbit anti-human SOSS complex subunit B2 polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SOSS. It may not necessarily be applicable to this product.

NCBI GI #

72534722

NCBI GeneID

64859

NCBI Accession #

NP_001026886.1

UniProt Primary Accession #

Q96AH0

UniProt Secondary Accession #

Q658Y8; Q9H5X6

UniProt Related Accession #

Q96AH0

GenBank Nucleotide #

NM_001031716.2

NCBI Official Full Name

SOSS complex subunit B2 isoform 1

NCBI Official Synonym Full Names

nucleic acid binding protein 1

NCBI Official Symbol

NABP1

NCBI Official Synonym Symbols

SSB2; OBFC2A; SOSS-B2

UniProt Protein Name

SOSS complex subunit B2

UniProt Synonym Protein Names

Protein Family

SOSS complex

UniProt Gene Name

NABP1

UniProt Synonym Gene Names

OBFC2A; SSB2; SOSS-B2; hSSB2

UniProt Entry Name

SOSB2_HUMAN

NCBI Protein Information

SOSS complex subunit B2

NCBI Summary for SOSS

Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2A, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 [PubMed 18449195]).[supplied by OMIM, Jun 2008]

UniProt Comments for SOSS

OBFC2A: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. Belongs to the SOSS-B family. SOSS-B2 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; DNA repair, damage; DNA-binding

Chromosomal Location of Human Ortholog: 2q32.3

Cellular Component: cytoplasm; nuclear chromosome, telomeric region; nucleoplasm; nucleus

Molecular Function: protein binding; RNA binding; single-stranded DNA binding

Biological Process: DNA repair; double-strand break repair via homologous recombination; mitotic cell cycle checkpoint; response to DNA damage stimulus; response to ionizing radiation

Research Articles on SOSS

1. hSSB1 and hSSB2 form two separate complexes with similar structures, and both complexes participate in DNA damage response.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SOSS antibody

Reference Product	PubMed Publications
NABP2 antibody	>3 publications with SOSS and NABP2
INTS3 antibody	>1 publications with SOSS and INTS3

Organs/Tissues associated with anti-SOSS antibody

Organ/Tissue Name	Pubmed Publications
Thymus Antibodies	>2 publications with SOSS and Thymus
Thyroid Antibodies	>1 publications with SOSS and Thyroid
Spleen Antibodies	>1 publications with SOSS and Spleen
Testis Antibodies	>1 publications with SOSS and Testis
Embryonic Tissue Antibodies	>1 publications with SOSS and Embryonic Tissue