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MTHFD2L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1493833

mitochondrion, methenyltetrahydrofolate cyclohydrolase activity, methylenetetrahydrofolate dehydrogenase (NAD+) activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity, one-carbon metabolic process More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MTHFD2L, Polyclonal Antibody
Full Product Name
MTHFD2L Antibody
Product Gene Name
anti-MTHFD2L antibody
Product Synonym Names
Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2; MTHFD2L; NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; MTHFD2-like; NAD-dependent methylenetetrahydrofolate dehydrogenase (EC:1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: MTHFD2L (MBS1493833)
FITC Conjugated Antibody: MTHFD2L (MBS1493447)
Matching Pairs
Unconjugated Antibody: MTHFD2L (MBS1493833)
Biotin Conjugated Antibody: MTHFD2L (MBS1494157)
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Molecular Weight
32,891 Da
OMIM
614047
3D Structure
ModBase 3D Structure for Q9H903
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 protein
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MTHFD2L antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-MTHFD2L antibody
Recommended dilution: WB:1:500-2000

Western Blot (WB) of anti-MTHFD2L antibody

Western blot
All lanes: MTHFD2L antibody at 6ug/ml+ Mouse lung tissue
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 38,32,8,25,33 kDa
Observed band size: 12 kDa
Rabbit Anti-MTHFD2L Polyclonal Antibody – Cat# MBS1493833

Other Notes

Small volumes of anti-MTHFD2L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MTHFD2L purchase

MBS1493833 is an antibody targeting MTHFD2L. Also known as MTHFD2L Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MTHFD2L. It may not necessarily be applicable to this product.

NCBI GI #
222418558
NCBI GeneID
441024
NCBI Accession #
NP_001138450.1
UniProt Primary Accession #
Q9H903
UniProt Secondary Accession #
Q6P079; Q8N560
UniProt Related Accession #
Q9H903
GenBank Nucleotide #
NM_001144978.1
NCBI Official Full Name
probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2
NCBI Official Synonym Full Names
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NCBI Official Symbol
MTHFD2L
UniProt Protein Name
Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2
UniProt Synonym Protein Names
NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; MTHFD2-like
Protein Family
Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase
UniProt Gene Name
MTHFD2L
UniProt Synonym Gene Names
MTHFD2-like
UniProt Entry Name
MTD2L_HUMAN
NCBI Protein Information
probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2

UniProt Comments for MTHFD2L

MTHFD2L: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.5.4.9; Hydrolase; Mitochondrial; Oxidoreductase; EC 1.5.1.15

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: mitochondrial inner membrane; mitochondrial matrix; mitochondrion

Molecular Function: formate-tetrahydrofolate ligase activity; methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NAD+) activity; methylenetetrahydrofolate dehydrogenase (NADP+) activity

Biological Process: 10-formyltetrahydrofolate metabolic process; folic acid and derivative biosynthetic process; histidine biosynthetic process; methionine biosynthetic process; one-carbon compound metabolic process; purine nucleotide biosynthetic process
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Research Articles on MTHFD2L

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MTHFD2L antibody

 Products by Pathway  Pathway Diagram
 C1-unit Interconversion, Eukaryotes Pathway antibodies  C1-unit Interconversion, Eukaryotes Pathway Diagram
 C1-unit Interconversion, Eukaryotes Pathway antibodies  C1-unit Interconversion, Eukaryotes Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
 One Carbon Pool By Folate Pathway antibodies  One Carbon Pool By Folate Pathway Diagram
 Trans-sulfuration And One Carbon Metabolism Pathway antibodies  Trans-sulfuration And One Carbon Metabolism Pathway Diagram

Organs/Tissues associated with anti-MTHFD2L antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >1 publications with MTHFD2L and Embryonic Tissue
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