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ACAD9 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1494449

Required for mitochondrial complex I assembly (PubMed:20816094, PubMed:24158852). Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active on palmitoyl-CoA than on stearoyl-CoA. However, it does not play a… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ACAD9, Polyclonal Antibody
Full Product Name
ACAD9 Antibody
Product Gene Name
anti-ACAD9 antibody
Product Synonym Names
ACAD-9; ACAD9
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
68,760 Da
OMIM
611103
3D Structure
ModBase 3D Structure for Q9H845
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Acyl-CoA dehydrogenase family member 9, mitochondrial protein (1-270aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-135148
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ACAD9 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ACAD9 antibody
Recommended dilution: WB:1:200-1000
IHC:1:20-1:200

Western Blot (WB) of anti-ACAD9 antibody

Western blot
All lanes: ACAD9 antibody at 6ug/ml
Lane 1:MCF-7 whole cell lysate
Lane 2:293T whole cell lysate
Lane 3:K562 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 69kDa
Observed band size: 69kDa
Rabbit Anti-ACAD9 Polyclonal Antibody – Cat# MBS1494449

Immunohistochemistry (IHC) of anti-ACAD9 antibody

Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS1494449 at dilution 1:100
Rabbit Anti-ACAD9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1494449

Immunohistochemistry (IHC) of anti-ACAD9 antibody

Immunohistochemistry of paraffin-embedded human colon cancer tissue using MBS1494449 at dilution 1:100
Rabbit Anti-ACAD9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1494449

Other Notes

Small volumes of anti-ACAD9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ACAD9 purchase

MBS1494449 is an antibody targeting ACAD9. Also known as ACAD9 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ACAD9. It may not necessarily be applicable to this product.

NCBI GI #
21361497
NCBI GeneID
28976
NCBI Accession #
NP_054768.2
UniProt Primary Accession #
Q9H845
UniProt Secondary Accession #
Q8WXX3; D3DNB8
UniProt Related Accession #
Q9H845
GenBank Nucleotide #
NM_014049.4
NCBI Official Full Name
acyl-CoA dehydrogenase family member 9, mitochondrial
NCBI Official Synonym Full Names
acyl-CoA dehydrogenase family member 9
NCBI Official Symbol
ACAD9
NCBI Official Synonym Symbols
NPD002
UniProt Protein Name
Acyl-CoA dehydrogenase family member 9, mitochondrial
Protein Family
Acyl-CoA dehydrogenase family
UniProt Gene Name
ACAD9
UniProt Synonym Gene Names
ACAD-9
UniProt Entry Name
ACAD9_HUMAN
NCBI Protein Information
acyl-CoA dehydrogenase family member 9, mitochondrial

NCBI Summary for ACAD9

This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]
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UniProt Comments for ACAD9

ACAD9: Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active on palmitoyl-CoA then on stearoyl-CoA. Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or isovaleryl-CoA (5:0). Belongs to the acyl-CoA dehydrogenase family.

Protein type: Mitochondrial; Oxidoreductase; EC 1.3.99.-

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: dendrite; mitochondrial inner membrane; mitochondrion; nucleus

Molecular Function: acyl-CoA binding; acyl-CoA dehydrogenase activity; electron carrier activity; FAD binding; protein binding

Biological Process: cellular metabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; lipid homeostasis; mitochondrial respiratory chain complex I assembly

Disease: Acyl-coa Dehydrogenase Family, Member 9, Deficiency Of
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Research Articles on ACAD9

1. Our results underscore the importance of the ACAD9 protein in complex I assembly and suggest that the enzymatic activity is a rudiment of the duplication event.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ACAD9 antibody

 Products by Pathway  Pathway Diagram
 Complex I Biogenesis Pathway antibodies  Complex I Biogenesis Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Respiratory Electron Transport Pathway antibodies  Respiratory Electron Transport Pathway Diagram
 Respiratory Electron Transport, ATP Synthesis By Chemiosmotic Coupling, And Heat Production By Uncoupling Proteins. Pathway antibodies  Respiratory Electron Transport, ATP Synthesis By Chemiosmotic Coupling, And Heat Production By Uncoupling Proteins. Pathway Diagram
 The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway antibodies  The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway Diagram

Diseases associated with anti-ACAD9 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >4 publications with ACAD9 and Fatty Liver
 Liver Diseases Antibodies  >3 publications with ACAD9 and Liver Diseases
 Acyl-CoA Dehydrogenase Family, Member 9, Deficiency of Antibodies  >3 publications with ACAD9 and Acyl-CoA Dehydrogenase Family, Member 9, Deficiency of
 Fetal Growth Retardation Antibodies  >1 publications with ACAD9 and Fetal Growth Retardation
 Cardiomegaly Antibodies  >1 publications with ACAD9 and Cardiomegaly
 Edema Antibodies  >1 publications with ACAD9 and Edema
 Hypertrophy Antibodies  >1 publications with ACAD9 and Hypertrophy
 Hyperplasia Antibodies  >1 publications with ACAD9 and Hyperplasia
 Necrosis Antibodies  >1 publications with ACAD9 and Necrosis

Organs/Tissues associated with anti-ACAD9 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >8 publications with ACAD9 and Muscle
 Brain Antibodies  >7 publications with ACAD9 and Brain
 Liver Antibodies  >5 publications with ACAD9 and Liver
 Heart Antibodies  >3 publications with ACAD9 and Heart
 Blood Antibodies  >2 publications with ACAD9 and Blood
 Nerve Antibodies  >1 publications with ACAD9 and Nerve
 Eye Antibodies  >1 publications with ACAD9 and Eye
 Kidney Antibodies  >1 publications with ACAD9 and Kidney
 Skin Antibodies  >1 publications with ACAD9 and Skin
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