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PMM1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1497555

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PMM1, Polyclonal Antibody
Full Product Name
PMM1 Antibody, FITC
Product Gene Name
anti-PMM1 antibody
Product Synonym Names
Phosphomannomutase 1; PMM 1; PMMH-22; PMM1; PMMH22
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: PMM1 (MBS7001010)
FITC Conjugated Antibody: PMM1 (MBS1497555)
Molecular Weight
29,747 Da
OMIM
601786
3D Structure
ModBase 3D Structure for Q92871
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
FITC
Immunogen
Recombinant human Phosphomannomutase 1 protrin(2-262aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-86200 / sc-86201
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PMM1 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-PMM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PMM1 purchase

MBS1497555 is an antibody targeting PMM1. Also known as PMM1 Antibody, FITC. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PMM1. It may not necessarily be applicable to this product.

NCBI GI #
194097356
NCBI GeneID
5372
NCBI Accession #
NP_002667.2
UniProt Primary Accession #
Q92871
UniProt Secondary Accession #
Q92586; A8K003
UniProt Related Accession #
Q92871
GenBank Nucleotide #
NM_002676.2
NCBI Official Full Name
phosphomannomutase 1
NCBI Official Synonym Full Names
phosphomannomutase 1
NCBI Official Symbol
PMM1
NCBI Official Synonym Symbols
Sec53
UniProt Protein Name
Phosphomannomutase 1
UniProt Synonym Protein Names
PMMH-22
Protein Family
Wasp kinin
UniProt Gene Name
PMM1
UniProt Synonym Gene Names
PMMH22; PMM 1
UniProt Entry Name
PMM1_HUMAN
NCBI Protein Information
phosphomannomutase 1

NCBI Summary for PMM1

Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008]
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UniProt Comments for PMM1

PMM1: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. Belongs to the eukaryotic PMM family.

Protein type: Isomerase; EC 5.4.2.8; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - fructose and mannose

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: cell soma; cytosol

Molecular Function: metal ion binding; phosphomannomutase activity; protein binding

Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; GDP-mannose biosynthetic process; mannose metabolic process; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine
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Research Articles on PMM1

1. PMM1 is responsible for the degradation of Glc-1,6-P(2) in brain

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PMM1 antibody

 Reference Product  PubMed Publications
 UBC antibody  >1 publications with PMM1 and UBC

Pathways associated with anti-PMM1 antibody

 Products by Pathway  Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway antibodies  Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 GDP-mannose Biosynthesis Pathway antibodies  GDP-mannose Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram

Diseases associated with anti-PMM1 antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with PMM1 and Disease Models, Animal
 Liver Diseases Antibodies  >2 publications with PMM1 and Liver Diseases
 Liver Neoplasms, Experimental Antibodies  >1 publications with PMM1 and Liver Neoplasms, Experimental
 Neoplasms, Experimental Antibodies  >1 publications with PMM1 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >1 publications with PMM1 and Liver Neoplasms

Organs/Tissues associated with anti-PMM1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with PMM1 and Brain
 Liver Antibodies  >5 publications with PMM1 and Liver
 Pancreas Antibodies  >3 publications with PMM1 and Pancreas
 Eye Antibodies  >2 publications with PMM1 and Eye
 Embryonic Tissue Antibodies  >2 publications with PMM1 and Embryonic Tissue
 Ovary Antibodies  >1 publications with PMM1 and Ovary
 Lung Antibodies  >1 publications with PMM1 and Lung
 Heart Antibodies  >1 publications with PMM1 and Heart
 Testis Antibodies  >1 publications with PMM1 and Testis
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