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APOBEC3C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1497829

DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the… More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
APOBEC3C, Polyclonal Antibody
Full Product Name
APOBEC3C Antibody
Product Gene Name
anti-APOBEC3C antibody
Product Synonym Names
DNA dC->dU-editing enzyme APOBEC-3C (A3C) (EC 3.5.4.-) (APOBEC1-like) (Phorbolin I), APOBEC3C, APOBEC1L PBI
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
OMIM
607750
3D Structure
ModBase 3D Structure for Q9NRW3
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Research Area
Epigenetics and Nuclear Signaling
Species
Human
Immunogen
Recombinant human DNA dC->dU-editing enzyme APOBEC-3C protein(1-190aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-46731 / sc-46732
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-APOBEC3C antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-APOBEC3C antibody
Recommended dilution: WB:1:200-1000
IHC:1:20-1:200

Western Blot (WB) of anti-APOBEC3C antibody

Western blot
All lanes: APOBEC3C antibody at 3ug/ml+K562 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 23kDa
Observed band size: 23kDa
Rabbit Anti-APOBEC3C Polyclonal Antibody – Cat# MBS1497829

Immunohistochemistry (IHC) of anti-APOBEC3C antibody

Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS1497829 at dilution 1:100
Rabbit Anti-APOBEC3C Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1497829

Other Notes

Small volumes of anti-APOBEC3C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APOBEC3C purchase

MBS1497829 is an antibody targeting APOBEC3C. Also known as APOBEC3C Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for APOBEC3C. It may not necessarily be applicable to this product.

NCBI GI #
22907039
NCBI GeneID
27350
NCBI Accession #
NP_055323.2
UniProt Primary Accession #
Q9NRW3
UniProt Secondary Accession #
Q5JZ92; Q7Z2N7; Q96F12; B2R884
UniProt Related Accession #
Q9NRW3
GenBank Nucleotide #
NM_014508.2
NCBI Official Full Name
DNA dC->dU-editing enzyme APOBEC-3C
NCBI Official Synonym Full Names
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C
NCBI Official Symbol
APOBEC3C
NCBI Official Synonym Symbols
A3C; PBI; ARP5; ARDC2; ARDC4; APOBEC1L; bK150C2.3
UniProt Protein Name
DNA dC->dU-editing enzyme APOBEC-3C
UniProt Synonym Protein Names
APOBEC1-like; Phorbolin I
Protein Family
DNA dC->dU-editing enzyme
UniProt Gene Name
APOBEC3C
UniProt Synonym Gene Names
APOBEC1L; PBI; A3C
UniProt Entry Name
ABC3C_HUMAN
NCBI Protein Information
DNA dC->dU-editing enzyme APOBEC-3C

NCBI Summary for APOBEC3C

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq, Jul 2008]
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UniProt Comments for APOBEC3C

APOBEC3C: Host cellular restriction factor that may have antiviral activities against exogenous and endogenous viruses, as well as retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. Belongs to the cytidine and deoxycytidylate deaminase family.

Protein type: EC 3.5.4.-; Hydrolase; RNA-binding

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cytoplasm; nucleus

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; protein binding; zinc ion binding

Biological Process: cytidine deamination; defense response to virus; innate immune response; negative regulation of viral genome replication; viral reproduction
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Research Articles on APOBEC3C

1. High APOBEC3C is associated with the pathogenesis of primary effusion lymphoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-APOBEC3C antibody

 Reference Product  PubMed Publications
 CUL5 antibody  >2 publications with APOBEC3C and CUL5
 APOBEC4 antibody  >1 publications with APOBEC3C and APOBEC4

Diseases associated with anti-APOBEC3C antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >2 publications with APOBEC3C and Carcinoma
 Carcinoma, Hepatocellular Antibodies  >2 publications with APOBEC3C and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >2 publications with APOBEC3C and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with APOBEC3C and Liver Diseases
 Adenocarcinoma Antibodies  >1 publications with APOBEC3C and Adenocarcinoma

Organs/Tissues associated with anti-APOBEC3C antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with APOBEC3C and Blood
 Liver Antibodies  >4 publications with APOBEC3C and Liver
 Kidney Antibodies  >2 publications with APOBEC3C and Kidney
 Brain Antibodies  >1 publications with APOBEC3C and Brain
 Vascular Antibodies  >1 publications with APOBEC3C and Vascular
 Prostate Antibodies  >1 publications with APOBEC3C and Prostate
 Lung Antibodies  >1 publications with APOBEC3C and Lung
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