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PAFAH1B2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1498342

Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PAFAH1B2, Polyclonal Antibody
Full Product Name
PAFAH1B2 Antibody, HRP conjugated
Product Gene Name
anti-PAFAH1B2 antibody
Product Synonym Names
Platelet-activating factor acetylhydrolase IB subunit beta (EC:3.1.1.47); PAFAH1B2; PAFAHB; PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH subunit beta
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: PAFAH1B2 (MBS1496851)
HRP Conjugated Antibody: PAFAH1B2 (MBS1498342)
Molecular Weight
22,734 Da
OMIM
602508
3D Structure
ModBase 3D Structure for P68402
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
HRP
Immunogen
Recombinant human Platelet-activating factor acetylhydrolase IB subunit beta protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-168889 / sc-168888
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PAFAH1B2 antibody
ELISA (EIA)

Other Notes

Small volumes of anti-PAFAH1B2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PAFAH1B2 purchase

MBS1498342 is an antibody targeting PAFAH1B2. Also known as PAFAH1B2 Antibody, HRP conjugated. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PAFAH1B2. It may not necessarily be applicable to this product.

NCBI GI #
296080766
NCBI GeneID
5049
NCBI Accession #
NP_001171675.1
UniProt Primary Accession #
P68402
UniProt Secondary Accession #
O00687; Q29459; Q6IBR6; A8DPS5; A8DPS6; A8DPS7; E9PEJ5; E9PLP3
UniProt Related Accession #
P68402
GenBank Nucleotide #
NM_001184746.1
NCBI Official Full Name
platelet-activating factor acetylhydrolase IB subunit beta isoform b
NCBI Official Synonym Full Names
platelet activating factor acetylhydrolase 1b catalytic subunit 2
NCBI Official Symbol
PAFAH1B2
NCBI Official Synonym Symbols
HEL-S-303
UniProt Protein Name
Platelet-activating factor acetylhydrolase IB subunit beta
UniProt Synonym Protein Names
PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH subunit beta
Protein Family
Platelet-activating factor acetylhydrolase
UniProt Gene Name
PAFAH1B2
UniProt Synonym Gene Names
PAFAHB; PAF-AH 30 kDa subunit; PAFAH subunit beta
UniProt Entry Name
PA1B2_HUMAN
NCBI Protein Information
platelet-activating factor acetylhydrolase IB subunit beta

NCBI Summary for PAFAH1B2

Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and LYSO-PAF. This gene encodes the beta subunit of PAFAH, the other subunits are alpha and gamma. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2014]
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UniProt Comments for PAFAH1B2

PAFAH1B2: Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipase; Motility/polarity/chemotaxis; Lipid Metabolism - ether lipid; EC 3.1.1.47; Acetyltransferase

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: cytoplasm; cytosol; nucleolus; plasma membrane

Molecular Function: 1-alkyl-2-acetylglycerophosphocholine esterase activity; platelet-activating factor acetyltransferase activity; protein heterodimerization activity; protein homodimerization activity

Biological Process: brain development; lipid catabolic process; lipid metabolic process; positive regulation of macroautophagy; spermatogenesis
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Research Articles on PAFAH1B2

1. PAFAH1B2 and 1B3 are important in maintaining cancer pathogenicity across a wide spectrum of cancer types.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PAFAH1B2 antibody

 Reference Product  PubMed Publications
 PAFAH1B3 antibody  >13 publications with PAFAH1B2 and PAFAH1B3
 PAFAH1B1 antibody  >8 publications with PAFAH1B2 and PAFAH1B1
 DAB1 antibody  >2 publications with PAFAH1B2 and DAB1
 NDEL1 antibody  >1 publications with PAFAH1B2 and NDEL1
 RELN antibody  >1 publications with PAFAH1B2 and RELN
 VLDLR antibody  >1 publications with PAFAH1B2 and VLDLR

Pathways associated with anti-PAFAH1B2 antibody

 Products by Pathway  Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway antibodies  Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram

Diseases associated with anti-PAFAH1B2 antibody

 Disease Name  Pubmed Publications
 Prostatic Diseases Antibodies  >1 publications with PAFAH1B2 and Prostatic Diseases
 Congenital Abnormalities Antibodies  >1 publications with PAFAH1B2 and Congenital Abnormalities
 Inflammation Antibodies  >1 publications with PAFAH1B2 and Inflammation

Organs/Tissues associated with anti-PAFAH1B2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with PAFAH1B2 and Brain
 Blood Antibodies  >4 publications with PAFAH1B2 and Blood
 Nerve Antibodies  >2 publications with PAFAH1B2 and Nerve
 Testis Antibodies  >2 publications with PAFAH1B2 and Testis
 Heart Antibodies  >2 publications with PAFAH1B2 and Heart
 Prostate Antibodies  >2 publications with PAFAH1B2 and Prostate
 Lung Antibodies  >1 publications with PAFAH1B2 and Lung
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