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FILIP1L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1499738

Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated… More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FILIP1L, Polyclonal Antibody
Full Product Name
FILIP1L Antibody
Product Gene Name
Product Synonym Names
Filamin A-interacting protein 1-like; FILIP1L; COL4A3BPIP; DOC1; GIP90; 130 kDa GPBP-interacting protein; 90 kDa GPBP-interacting protein; Protein down-regulated in ovarian cancer 1; DOC-1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: FILIP1L (MBS1499738)
FITC Conjugated Antibody: FILIP1L (MBS1493573)
Matching Pairs
Unconjugated Antibody: FILIP1L (MBS1499738)
Biotin Conjugated Antibody: FILIP1L (MBS1495096)
Molecular Weight
102,441 Da
OMIM
612993
3D Structure
ModBase 3D Structure for Q4L180
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Filamin A-interacting protein 1-like protein
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-FILIP1L antibody
ELISA (EIA), Immunohistochemistry (IHC)

Western Blot (WB) of anti-FILIP1L antibody

Western Blot
Positive WB detected in: Rat stomach tissue, Mouse kidney tissue
All lanes: FILIP1L antibody at 2.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 131,103,30,100,80 KDa
Observed band size: 131 KDa
Rabbit Anti-FILIP1L Polyclonal Antibody – Cat# MBS1499738

Immunohistochemistry (IHC) of anti-FILIP1L antibody

Immunohistochemistry of paraffin-embedded human colon cancer using MBS1499738 at dilution of 1:100
Rabbit Anti-FILIP1L Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1499738

Immunohistochemistry (IHC) of anti-FILIP1L antibody

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS1499738 at dilution of 1:100
Rabbit Anti-FILIP1L Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS1499738

Immunofluorescence (IF) of anti-FILIP1L antibody

Immunofluorescence staining of HepG2 cells with MBS1499738 at 1:166,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 degree C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Rabbit Anti-FILIP1L Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS1499738

Other Notes

Small volumes of anti-FILIP1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FILIP1L purchase

MBS1499738 is an antibody targeting FILIP1L. Also known as FILIP1L Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FILIP1L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
filamin A-interacting protein 1-like isoform 3
NCBI Official Synonym Full Names
filamin A interacting protein 1-like
NCBI Official Symbol
FILIP1L
NCBI Official Synonym Symbols
DOC1; DOC-1; GIP90; GIP130
UniProt Protein Name
Filamin A-interacting protein 1-like
UniProt Synonym Protein Names
130 kDa GPBP-interacting protein; 90 kDa GPBP-interacting protein; Protein down-regulated in ovarian cancer 1; DOC-1
UniProt Gene Name
FILIP1L
UniProt Synonym Gene Names
COL4A3BPIP; DOC1; GIP90; DOC-1
UniProt Entry Name
FIL1L_HUMAN
NCBI Protein Information
filamin A-interacting protein 1-like

UniProt Comments for FILIP1L

FILIP1L: Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor- associated vasculature. Belongs to the FILIP1 family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 3q12.1

Cellular Component: cytoplasm; membrane; nucleus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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