• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MEX3B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150066

RKHD3 Antibody: Rkhd3, also known as MEX3B is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins,… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RKHD3 (MEX3B), Polyclonal Antibody
Full Product Name
RKHD3 Antibody
Product Gene Name
anti-MEX3B antibody
Product Synonym Names
RKHD3; RKHD3; MEX-3B; RNF195; KIAA2009; RKHD3; RNA-binding protein MEX3B; RING finger and KH domain-containing protein 3; mex-3 homolog B
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
RKHD3 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
This antibody is specific for RKHD3 and will not recognize the other RKHD3 family of proteins.
Preparation and Storage
RKHD3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
Rkhd3 peptide (MBS152778) is used for blocking the activity of RKHD3 antibody (MBS150066)
Molecular Weight
16,780 Da
OMIM
611008
3D Structure
ModBase 3D Structure for Q6ZN04
Conjugate
Unconjugated
Immunogen
RKHD3 antibody was raised against a 16 amino acid synthetic peptide from near the center of human RKHD3.
Buffer
RKHD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-MEX3B antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-MEX3B antibody
RKHD3 antibody can be used for detection of EPAC1 by Western blot at 1 mug/mL. Antibody can also be used for immunofluorescence starting at 20 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-MEX3B antibody

Western blot analysis of RKHD3 in human testis tissue lysate with RKHD3 antibody at 1 μg/mL.
Rabbit Anti-MEX3B Polyclonal Antibody – Cat# MBS150066

Immunofluorescence (IF) of anti-MEX3B antibody

Immunofluorescence of RKHD3 in mouse skeletal muscle cells with RKHD3 antibody at 20 μg/mL.
Rabbit Anti-MEX3B Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150066

Other Notes

Small volumes of anti-MEX3B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MEX3B purchase

MBS150066 is an antibody targeting MEX3B. Also known as RKHD3 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MEX3B. It may not necessarily be applicable to this product.

NCBI GI #
47716512
NCBI GeneID
84206
NCBI Accession #
NP_780575
UniProt Primary Accession #
Q6ZN04
UniProt Secondary Accession #
Q4G0W1; Q8IVG2; Q9H0J0
UniProt Related Accession #
Q6ZN04
GenBank Nucleotide #
NM_032246.4
NCBI Official Full Name
RNA-binding protein MEX3B
NCBI Official Synonym Full Names
mex-3 RNA binding family member B
NCBI Official Symbol
MEX3B
NCBI Official Synonym Symbols
RKHD3; MEX-3B; RNF195
UniProt Protein Name
RNA-binding protein MEX3B
UniProt Synonym Protein Names
RING finger and KH domain-containing protein 3; RING finger protein 195
Protein Family
RNA-binding protein
UniProt Gene Name
MEX3B
UniProt Synonym Gene Names
KIAA2009; RKHD3; RNF195
UniProt Entry Name
MEX3B_HUMAN
NCBI Protein Information
RNA-binding protein MEX3B; RING finger protein 195; ring finger and KH domain containing 3

NCBI Summary for MEX3B

This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies. [provided by RefSeq, Oct 2012]
Show more

UniProt Comments for MEX3B

RKHD3: RNA-binding protein. May be involved in post- transcriptional regulatory mechanisms. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 15q25.2

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: zinc ion binding; calcium ion binding

Biological Process: protein amino acid autophosphorylation; protein amino acid phosphorylation
Show more

Research Articles on MEX3B

1. 14-3-3 exerts combined effects on hMex-3B and acts as a major regulator of the sorting between distinct classes of RNA granules

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MEX3B antibody

 Reference Product  PubMed Publications
 EIF2C1 antibody  >1 publications with MEX3B and EIF2C1

Organs/Tissues associated with anti-MEX3B antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >1 publications with MEX3B and Embryonic Tissue
 Testis Antibodies  >1 publications with MEX3B and Testis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000