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NLRP5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150106

NALP5 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NALP5 (NLRP5), Polyclonal Antibody
Full Product Name
NALP5 Antibody
Product Gene Name
Product Synonym Names
NALP5; MATER; NALP5; PAN11; PYPAF8; CLR19.8; MATER; NACHT; LRR and PYD domains-containing protein 5; Mater protein homolog; NLR family, pyrin domain containing 5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
NALP5 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
NALP5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
NALP5 peptide (MBS152825) is used for blocking the activity of NALP5 antibody (MBS150106)
Molecular Weight
134,342 Da
OMIM
609658
3D Structure
ModBase 3D Structure for P59047
Conjugate
Unconjugated
Immunogen
NALP5 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human NALP5.
Buffer
NALP5 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-NLRP5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-NLRP5 antibody
NALP5 antibody can be used for detection of NALP5 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-NLRP5 antibody

Western blot analysis of NALP5 in mouse brain tissue lysate with NALP5 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-NLRP5 Polyclonal Antibody – Cat# MBS150106

Immunohistochemistry (IHC) of anti-NLRP5 antibody

Immunohistochemistry of NALP5 in human brain tissue with NALP5 antibody at 10 μg/mL.
Rabbit Anti-NLRP5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150106

Immunofluorescence (IF) of anti-NLRP5 antibody

Immunofluorescence of NALP5 in human brain tissue with NALP5 antibody at 20 μg/mL.
Rabbit Anti-NLRP5 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150106

Other Notes

Small volumes of anti-NLRP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NLRP5 purchase

MBS150106 is an antibody targeting NLRP5. Also known as NALP5 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NLRP5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
NACHT, LRR and PYD domains-containing protein 5
NCBI Official Synonym Full Names
NLR family, pyrin domain containing 5
NCBI Official Symbol
NLRP5
NCBI Official Synonym Symbols
MATER; NALP5; PAN11; PYPAF8; CLR19.8
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 5
UniProt Synonym Protein Names
Mater protein homolog
UniProt Gene Name
NLRP5
UniProt Synonym Gene Names
MATER; NALP5
UniProt Entry Name
NALP5_HUMAN
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 5; mater protein homolog; maternal antigen that embryos require; NACHT, leucine rich repeat and PYD containing 5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5

NCBI Summary for NLRP5

The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008]
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UniProt Comments for NLRP5

NLRP5: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. Belongs to the NLRP family.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 19q13.43

Cellular Component: protein complex; apical cortex; mitochondrion; nucleolus; cytosol

Molecular Function: ATP binding

Biological Process: regulation of RNA stability; organ morphogenesis; fertilization; cellular protein complex assembly; in utero embryonic development; regulation of protein stability; embryo implantation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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