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CPEB1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150196

CPEB1 Antibody: CPEB1 is an RNA binding protein that contains an RNA-recognition motif and a zinc finger-containing region found in a wide range of vertebrates and invertebrates. CPEB1 forms the nucleus of a complex of factors that regulate poly(A) elongation… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CPEB1, Polyclonal Antibody
Full Product Name
CPEB1 Antibody
Product Gene Name
Product Synonym Names
CPEB1; CEBP; CPEB; CPEB-1; CPE-BP1; hCPEB-1; Cytoplasmic polyadenylation element-binding protein 1; cytoplasmic polyadenylation element binding protein 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid; CPEB1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purity/Purification
CPEB1 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
CPEB1 antibody can be stored at 4°C for three months and -204°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
CPEB1 peptide (MBS152396) is used for blocking the activity of CPEB1 antibody (MBS150196)
OMIM
607342
3D Structure
ModBase 3D Structure for Q9BZB8
Conjugate
Unconjugated
Immunogen
CPEB1 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human CPEB1. The immunogen is located within amino acids 50-100 of CPEB1.
Positive Control
MBS151758 - Rat Brain Tissue Lysate
Applications Tested/Suitable for anti-CPEB1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-CPEB1 antibody
CPEB1 antibody can be used for detection of CPEB1 by Western blot at 1 - 2 mug/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Western Blot (WB) of anti-CPEB1 antibody

Western blot analysis of CPEB1 in rat brain tissue lysate with CPEB1 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-CPEB1 Polyclonal Antibody – Cat# MBS150196

Other Notes

Small volumes of anti-CPEB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CPEB1 purchase

MBS150196 is an antibody targeting CPEB1. Also known as CPEB1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CPEB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Cytoplasmic polyadenylation element-binding protein 1
NCBI Official Synonym Full Names
cytoplasmic polyadenylation element binding protein 1
NCBI Official Symbol
CPEB1
NCBI Official Synonym Symbols
CPEB; CPEB-1; CPE-BP1; hCPEB-1
UniProt Protein Name
Cytoplasmic polyadenylation element-binding protein 1
UniProt Gene Name
CPEB1
UniProt Synonym Gene Names
CPEB; CPE-BP1; CPE-binding protein 1; h-CEBP; hCPEB-1
UniProt Entry Name
CPEB1_HUMAN
NCBI Protein Information
cytoplasmic polyadenylation element-binding protein 1; CPE-binding protein 1

NCBI Summary for CPEB1

This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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UniProt Comments for CPEB1

CPEB: cytoplasmic polyadenylation element binding protein 1. Binds to the protein CPE and drives its polyadenylation. Activated by the protein kinase AurA. Insulin and progesterone stimulate AurA-catalyzed phosphorylation of CPEB in oocytes. Neuronal CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia.

Protein type: Translation; RNA-binding

Chromosomal Location of Human Ortholog: 15q25.2

Cellular Component: postsynaptic membrane; dendrite; postsynaptic density; cytoplasm; nucleus; cell junction

Molecular Function: metal ion binding; translation repressor activity, nucleic acid binding; nucleotide binding

Biological Process: synaptonemal complex assembly; cellular response to insulin stimulus; mRNA processing; regulation of neuronal synaptic plasticity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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