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SEC62 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150395

SEC62 Antibody: SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane. It is speculated that… More details

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Product Overview

Online Datasheet in PDF
Product Name
SEC62, Polyclonal Antibody
Full Product Name
SEC62 Antibody
Product Gene Name
Product Synonym Names
SEC62; HTP1; TP-1; Dtrp1; TLOC1; Translocation protein SEC62; Translocation protein 1; SEC62 homolog (S. cerevisiae)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
SEC62 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
SEC62 antibody is predicted to not cross-react with other SEC proteins. Multiple isoforms of SEC62 are known to exist.
Preparation and Storage
SEC62 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
SEC62 peptide (MBS152015) is used for blocking the activity of SEC62 antibody (MBS150395)
Molecular Weight
45,862 Da
OMIM
602173
3D Structure
ModBase 3D Structure for Q99442
Conjugate
Unconjugated
Immunogen
SEC62 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SEC62.
Buffer
SEC62 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-SEC62 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-SEC62 antibody
SEC62 antibody can be used for detection of SEC62 by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-SEC62 antibody

Western blot analysis of SEC62 in rat brain tissue lysate with SEC62 antibody at (A) 0.5 and (B) 1 μg/mL.
Rabbit Anti-SEC62 Polyclonal Antibody – Cat# MBS150395

Immunohistochemistry (IHC) of anti-SEC62 antibody

Immunohistochemistry of SEC62 in mouse brain tissue with SEC62 antibody at 5 μg/mL.
Rabbit Anti-SEC62 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150395

Immunofluorescence (IF) of anti-SEC62 antibody

Immunofluorescence of SEC62 in mouse brain tissue with SEC62 antibody at 20 μg/mL.
Rabbit Anti-SEC62 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150395

Other Notes

Small volumes of anti-SEC62 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEC62 purchase

MBS150395 is an antibody targeting SEC62. Also known as SEC62 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SEC62. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
translocation protein SEC62
NCBI Official Synonym Full Names
SEC62 homolog (S. cerevisiae)
NCBI Official Symbol
SEC62
NCBI Official Synonym Symbols
HTP1; TP-1; Dtrp1; TLOC1
UniProt Protein Name
Translocation protein SEC62
UniProt Synonym Protein Names
Translocation protein 1; TP-1; hTP-1
Protein Family
UniProt Gene Name
SEC62
UniProt Synonym Gene Names
TLOC1; TP-1; hTP-1
UniProt Entry Name
SEC62_HUMAN
NCBI Protein Information
translocation protein SEC62; hTP-1; translocation protein 1; membrane protein SEC62, S.cerevisiae, homolog of

NCBI Summary for SEC62

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
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UniProt Comments for SEC62

SEC62: a multi-pass membrane protein and component of the Sec61 complex of the rough endoplasmic reticulum membrane. The Sec61 complex may perform post-translational protein translocation into the ER and backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Channel, misc.; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 3q26.2

Cellular Component: intermediate filament cytoskeleton; endoplasmic reticulum membrane; rough endoplasmic reticulum; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: receptor activity; protein transporter activity

Biological Process: posttranslational protein targeting to membrane; cotranslational protein targeting to membrane
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SEC62 antibody

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