• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Kappab Ras1 (NKIRAS1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150526

KappaB ras1 Antibody: KappaB ras-1 (κB-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IκB (IκB), an inhibitor of the transcription factor NF-κB. IκB exists in two homologous forms, IκB-alpha and… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KappaB ras1 (NKIRAS1), Polyclonal Antibody
Full Product Name
KappaB ras1 Antibody
Product Gene Name
anti-NKIRAS1 antibody
Product Synonym Names
KappaB ras1; KBRAS1; kappaB-Ras1; KBRAS1; NF-kappa-B inhibitor-interacting Ras-like protein 1; I-kappa-B-interacting Ras-like protein 1; Kappa B-Ras protein 1; NFKB inhibitor interacting Ras-like 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
KappaB ras1 Antibody is affinity chromatography purified via peptide column.
Preparation and Storage
KappaB ras1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
KappaB ras1 peptide (MBS152288) is used for blocking the activity of KappaB ras1 antibody (MBS150526)
Molecular Weight
21,643 Da
OMIM
604496
3D Structure
ModBase 3D Structure for Q9NYS0
Conjugate
Unconjugated
Immunogen
KappaB ras1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human KappaB ras1.
Buffer
KappaB ras1 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-NKIRAS1 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-NKIRAS1 antibody
KappaB ras1 antibody can be used for detection of KappaB ras1 by Western blot at 0.5 - 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 1 mug/mL.

Western Blot (WB) of anti-NKIRAS1 antibody

Western blot analysis of KappaB ras1 in RAW264.7 cell lysate with KappaB ras1 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.
Rabbit Anti-NKIRAS1 Polyclonal Antibody – Cat# MBS150526

Immunocytochemistry (IHC) of anti-NKIRAS1 antibody

Immunocytochemistry of KappaB-ras1 in RAW264.7 cells with KappaB-ras1 antibody at 1 μg/mL.
Rabbit Anti-NKIRAS1 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS150526

Other Notes

Small volumes of anti-NKIRAS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NKIRAS1 purchase

MBS150526 is an antibody targeting NKIRAS1. Also known as KappaB ras1 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NKIRAS1. It may not necessarily be applicable to this product.

NCBI GI #
7008402
NCBI GeneID
28512
NCBI Accession #
AAF34998
UniProt Primary Accession #
Q9NYS0
UniProt Secondary Accession #
Q96K18
UniProt Related Accession #
Q9NYS0
NCBI Official Full Name
kappa B-ras 1
NCBI Official Synonym Full Names
NFKB inhibitor interacting Ras-like 1
NCBI Official Symbol
NKIRAS1
NCBI Official Synonym Symbols
KBRAS1; kappaB-Ras1
UniProt Protein Name
NF-kappa-B inhibitor-interacting Ras-like protein 1
UniProt Synonym Protein Names
I-kappa-B-interacting Ras-like protein 1; Kappa B-Ras protein 1; KappaB-Ras1
Protein Family
NF-kappa-B inhibitor-interacting Ras-like protein
UniProt Gene Name
NKIRAS1
UniProt Synonym Gene Names
KBRAS1; Kappa B-Ras protein 1; KappaB-Ras1
UniProt Entry Name
KBRS1_HUMAN
NCBI Protein Information
NF-kappa-B inhibitor-interacting Ras-like protein 1; kappa B-ras 1; kappa B-Ras protein 1; I-kappa-B-interacting Ras-like protein 1; NFKB inhibitor interacting Ras-like protein 1

UniProt Comments for NKIRAS1

NKIRAS1: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

Protein type: G protein; G protein, monomeric, Ras; G protein, monomeric

Chromosomal Location of Human Ortholog: 3p24.2

Cellular Component: membrane; cytoplasm

Molecular Function: GTPase activity; GTP binding

Biological Process: I-kappaB kinase/NF-kappaB cascade; metabolic process; small GTPase mediated signal transduction
Show more

Research Articles on NKIRAS1

1. Significant correlation was found between alterations of methylation status of miR-34b/c, miR-193a and the expression level of NKIRAS1 target gene in the primary lung tumors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NKIRAS1 antibody

 Products by Pathway  Pathway Diagram
 TNF-alpha/NF-kB Signaling Pathway antibodies  TNF-alpha/NF-kB Signaling Pathway Diagram

Diseases associated with anti-NKIRAS1 antibody

 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >2 publications with NKIRAS1 and Lung Neoplasms
 Adenocarcinoma Antibodies  >2 publications with NKIRAS1 and Adenocarcinoma
 Kidney Diseases Antibodies  >1 publications with NKIRAS1 and Kidney Diseases

Organs/Tissues associated with anti-NKIRAS1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >2 publications with NKIRAS1 and Lung
 Placenta Antibodies  >1 publications with NKIRAS1 and Placenta
 Kidney Antibodies  >1 publications with NKIRAS1 and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000