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RUSC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150564

RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130,… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RUSC2, Polyclonal Antibody
Full Product Name
RUSC2 Antibody
Product Gene Name
Product Synonym Names
RUSC2; Iporin; KIAA0375; Iporin; Interacting protein of Rab1; RUN and SH3 domain containing 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
RUSC2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least three isoforms are known to exist; this antibody will only detect the longest isoform. This antibody is predicted to not cross-react with RUSC1.
Preparation and Storage
RUSC2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
RUSC2 peptide (MBS153279) is used for blocking the activity of RUSC2 antibody (MBS150564)
Molecular Weight
161,225 Da
OMIM
611053
3D Structure
ModBase 3D Structure for Q8N2Y8
Conjugate
Unconjugated
Immunogen
RUSC2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RUSC2.
Buffer
RUSC2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-RUSC2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-RUSC2 antibody
RUSC2 antibody can be used for detection of RUSC2 by immunohistrochemistry at 5 mug/mL.

Immunohistochemistry (IHC) of anti-RUSC2 antibody

Immunohistochemistry of RUSC2 in human placenta tissue with RUSC2 antibody at 5 μg/mL.
Rabbit Anti-RUSC2 Polyclonal Antibody – Cat# MBS150564

Other Notes

Small volumes of anti-RUSC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RUSC2 purchase

MBS150564 is an antibody targeting RUSC2. Also known as RUSC2 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RUSC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
iporin
NCBI Official Synonym Full Names
RUN and SH3 domain containing 2
NCBI Official Symbol
RUSC2
NCBI Official Synonym Symbols
Iporin
UniProt Protein Name
Iporin
UniProt Synonym Protein Names
Interacting protein of Rab1; RUN and SH3 domain-containing protein 2
Protein Family
UniProt Gene Name
RUSC2
UniProt Synonym Gene Names
KIAA0375
UniProt Entry Name
RUSC2_HUMAN
NCBI Protein Information
iporin; interacting protein of Rab1; RUN and SH3 domain-containing protein 2

NCBI Summary for RUSC2

This gene encodes a RUN and SH3 domain containing protein that interacts with Rab1b and Rab1-binding protein GM130. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2012]

UniProt Comments for RUSC2

RUSC2: Interacts with active RAB1A and RAB1B, and with GOLGA2.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 9p13.3

Cellular Component: cytoplasmic vesicle; cytosol

Molecular Function: protein binding; Rab GTPase binding

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RUSC2 antibody

Diseases associated with anti-RUSC2 antibody

Organs/Tissues associated with anti-RUSC2 antibody

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