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PDCD1LG2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151188

PDL-2 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PDL-2 (PDCD1LG2), Polyclonal Antibody
Full Product Name
PDL-2 Antibody
Product Gene Name
Product Synonym Names
PDL-2; B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; B7DC; Programmed cell death 1 ligand 2; Butyrophilin B7-DC; PD-1 ligand 2; programmed cell death 1 ligand 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
PDL-2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
PDL-2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
PDL-2 peptide (MBS153072) is used for blocking the activity of PDL-2 antibody (MBS151188)
Molecular Weight
Predicted: 30 kDa

Observed: 32 kDa
OMIM
605723
3D Structure
ModBase 3D Structure for Q9BQ51
Conjugate
Unconjugated
Immunogen
PDL-2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human PDL-2.
Buffer
PDL-2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-PDCD1LG2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-PDCD1LG2 antibody
PDL-2 antibody can be used for detection of PDL-2 by Western blot at 0.5 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-PDCD1LG2 antibody

Western blot analysis of PD-L2 in Raji cell lysate with PD-L2 antibody at 0.5 and 1 μg/mL.
Rabbit Anti-PDCD1LG2 Polyclonal Antibody – Cat# MBS151188

Immunohistochemistry (IHC) of anti-PDCD1LG2 antibody

Immunohistochemistry of PD-L2 in mouse brain tissue with PD-L2 antibody at 2.5 μg/mL.
Rabbit Anti-PDCD1LG2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151188

Immunofluorescence (IF) of anti-PDCD1LG2 antibody

Immunofluorescence of PD-L2 in Mouse Brain cells with PD-L2 antibody at 20 μg/mL.
Rabbit Anti-PDCD1LG2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151188

Immunohistochemistry (IHC) of anti-PDCD1LG2 antibody

Immunohistochemistry of PD-L2 in mouse brain tissue with PD-L2 antibody at 2.5 μg/ml.
Rabbit Anti-PDCD1LG2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151188

Immunofluorescence (IF) of anti-PDCD1LG2 antibody

Immunofluorescence of PD-L2 in mouse brain tissue with PD-L2 antibody at 20 μg/ml.
Rabbit Anti-PDCD1LG2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151188

Immunofluorescence (IF) of anti-PDCD1LG2 antibody

Immunofluorescence of PD-L2 in mouse brain tissue with PD-L2 antibody at 20 μg/ml.

Green: PD-L2 Antibody (4063)
Blue: DAPI staining
Rabbit Anti-PDCD1LG2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151188

Other Notes

Small volumes of anti-PDCD1LG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDCD1LG2 purchase

MBS151188 is an antibody targeting PDCD1LG2. Also known as PDL-2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDCD1LG2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
programmed cell death 1 ligand 2
NCBI Official Synonym Full Names
programmed cell death 1 ligand 2
NCBI Official Symbol
PDCD1LG2
NCBI Official Synonym Symbols
B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2
UniProt Protein Name
Programmed cell death 1 ligand 2
UniProt Synonym Protein Names
Butyrophilin B7-DC; B7-DC; CD_antigen: CD273
Protein Family
UniProt Gene Name
PDCD1LG2
UniProt Synonym Gene Names
B7DC; CD273; PDCD1L2; PDL2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC
UniProt Entry Name
PD1L2_HUMAN
NCBI Protein Information
programmed cell death 1 ligand 2; B7-DC; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2; B7 dendritic cell molecule

UniProt Comments for PDCD1LG2

PDCD1LG2: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 9p24.2

Cellular Component: plasma membrane; integral to membrane; endomembrane system

Biological Process: negative regulation of interleukin-10 production; negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; T cell costimulation; immune response; positive regulation of T cell proliferation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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