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SLC39A3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151229

ZIP3 Antibody: The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ZIP3 (SLC39A3), Polyclonal Antibody
Full Product Name
ZIP3 Antibody
Product Gene Name
anti-SLC39A3 antibody
Product Synonym Names
ZIP3; ZIP3; ZIP-3; ZIP3; Zinc transporter ZIP3; Solute carrier family 39 member 3; solute carrier family 39 (zinc transporter), member 3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
ZIP3 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
ZIP3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
ZIP3 peptide (MBS152286) is used for blocking the activity of ZIP3 antibody (MBS151229)
Molecular Weight
11,459 Da
OMIM
612168
3D Structure
ModBase 3D Structure for Q9BRY0
Conjugate
Unconjugated
Immunogen
ZIP3 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP3.
Buffer
ZIP3 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-SLC39A3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SLC39A3 antibody
ZIP3 antibody can be used for detection of ZIP3 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL.

Western Blot (WB) of anti-SLC39A3 antibody

Western blot analysis of ZIP3 in mouse lung tissue lysate with ZIP3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-SLC39A3 Polyclonal Antibody – Cat# MBS151229

Immunohistochemistry (IHC) of anti-SLC39A3 antibody

Immunohistochemistry of ZIP3 in mouse lung tissue with ZIP3 antibody at 5 μg/mL.
Rabbit Anti-SLC39A3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151229

Other Notes

Small volumes of anti-SLC39A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC39A3 purchase

MBS151229 is an antibody targeting SLC39A3. Also known as ZIP3 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC39A3. It may not necessarily be applicable to this product.

NCBI GI #
32490561
NCBI GeneID
29985
NCBI Accession #
NP_653165
UniProt Primary Accession #
Q9BRY0
UniProt Secondary Accession #
Q8WUG1; B3KMJ3
UniProt Related Accession #
Q9BRY0
GenBank Nucleotide #
NM_144564.4
NCBI Official Full Name
zinc transporter ZIP3 isoform a
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 3
NCBI Official Symbol
SLC39A3
NCBI Official Synonym Symbols
ZIP3; ZIP-3
UniProt Protein Name
Zinc transporter ZIP3
UniProt Synonym Protein Names
Solute carrier family 39 member 3; Zrt- and Irt-like protein 3; ZIP-3
Protein Family
Zinc transporter
UniProt Gene Name
SLC39A3
UniProt Synonym Gene Names
ZIP3; ZIP-3
UniProt Entry Name
S39A3_HUMAN
NCBI Protein Information
zinc transporter ZIP3; zrt- and Irt-like protein 3; solute carrier family 39 member 3

UniProt Comments for SLC39A3

SLC39A3: Acts as a zinc-influx transporter (Potential). Belongs to the ZIP transporter (TC 2.A.5) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: plasma membrane; integral to membrane

Molecular Function: zinc ion transmembrane transporter activity

Biological Process: transmembrane transport
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Research Articles on SLC39A3

1. These results support a concept that downregulation of RREB-1 causes downregulation of ZIP3, which results in decreased zinc in pancreatic premalignant and carcinoma cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC39A3 antibody

 Reference Product  PubMed Publications
 SLC30A5 antibody  >2 publications with SLC39A3 and SLC30A5
 SLC39A4 antibody  >2 publications with SLC39A3 and SLC39A4
 SLC30A4 antibody  >2 publications with SLC39A3 and SLC30A4

Pathways associated with anti-SLC39A3 antibody

 Products by Pathway  Pathway Diagram
 Metal Ion SLC Transporters Pathway antibodies  Metal Ion SLC Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
 Zinc Influx Into Cells By The SLC39 Gene Family Pathway antibodies  Zinc Influx Into Cells By The SLC39 Gene Family Pathway Diagram
 Zinc Transporters Pathway antibodies  Zinc Transporters Pathway Diagram

Diseases associated with anti-SLC39A3 antibody

 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >2 publications with SLC39A3 and Prostatic Neoplasms
 Inflammation Antibodies  >2 publications with SLC39A3 and Inflammation
 Precancerous Conditions Antibodies  >1 publications with SLC39A3 and Precancerous Conditions
 Growth Disorders Antibodies  >1 publications with SLC39A3 and Growth Disorders
 Nerve Degeneration Antibodies  >1 publications with SLC39A3 and Nerve Degeneration
 Craniofacial Abnormalities Antibodies  >1 publications with SLC39A3 and Craniofacial Abnormalities
 Necrosis Antibodies  >1 publications with SLC39A3 and Necrosis

Organs/Tissues associated with anti-SLC39A3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with SLC39A3 and Blood
 Brain Antibodies  >5 publications with SLC39A3 and Brain
 Embryonic Tissue Antibodies  >4 publications with SLC39A3 and Embryonic Tissue
 Intestine Antibodies  >4 publications with SLC39A3 and Intestine
 Mammary Gland Antibodies  >4 publications with SLC39A3 and Mammary Gland
 Pancreas Antibodies  >4 publications with SLC39A3 and Pancreas
 Muscle Antibodies  >3 publications with SLC39A3 and Muscle
 Liver Antibodies  >3 publications with SLC39A3 and Liver
 Prostate Antibodies  >2 publications with SLC39A3 and Prostate
 Kidney Antibodies  >2 publications with SLC39A3 and Kidney
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